ArticleRadiology and oncology2023
Oral verrucous carcinoma: a diagnostic and therapeutic challenge.
Article in Radiology and oncology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 28 citations in OpenAlex.
- Quercetin as a Therapeutic Agent for Oral Cancer: Current Evidence and Future Directions.Asia-Pacific journal of clinical oncology · 2026Review
- Clinical and Histopathological Features of Oral Verruciform Xanthoma: A Case Series of Three Patients.Clinical case reports · 2026Article
- The progression of proliferative verrucous leukoplakia can be detected through elevated levels of salivary matrix metalloproteinases.BMC oral health · 2026Article
- Proliferative verrucous leukoplakia management requires x-ray surveillance. A retrospective study of 78 cases.Clinical oral investigations · 2026Article
- Perineal Verrucous Carcinoma Associated With Hypercalcemia: First Clinical Report of Parathyroid Hormone-Related Protein-producing Tumor.Plastic and reconstructive surgery. Global open · 2026Article
- Verrucous Carcinoma of the Lower Lip: A Rare Case Mimicking Benign Lesion.Journal of clinical medicine · 2025Article
- Article
- Review
- Accuracy of ChatGPT 3.5, 4.0, 4o and Gemini in diagnosing oral potentially malignant lesions based on clinical case reports and image recognition.Medicina oral, patologia oral y cirugia bucal · 2025Article
- Histopathological Variants of Oral Squamous Cell Carcinoma Operated at a Cancer Institute in North India.Indian journal of surgical oncology · 2024Article
- Comparison of E-Cadherin Expression in Oral Verrucous Carcinoma and Normal Oral Mucosa: An Immunohistochemical Study.Cureus · 2024Article
- Molecular Targets of Plant-Derived Bioactive Compounds in Oral Squamous Cell Carcinoma.Cancers · 2024Review
- Review
- Classificatory updates in verrucous and cuniculatum carcinomas: Insights from the 5World journal of clinical oncology · 2024Article
- Evaluation of Tumor-Associated Macrophages and Micro-Vessel Density in Verrucous Carcinoma and Squamous Cell Carcinoma of the Oral Cavity.Advanced biomedical research · 2024Article
- Protocol for Treatment of Oral Verrucous Carcinoma - A Systematic Review and Meta-Analysis.Annals of maxillofacial surgeryReview
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundVerrucous carcinoma is a low-grade variant of squamous cell carcinoma with specific morphologic, cytokinetic and clinical features. Despite low mitotic activity and slow growth, it can infiltrate adjacent tissues in advanced stages but does not metastasize. The most frequently affected site is the oral cavity. The following article provides latest updates in the etiology, clinical presentation, diagnostics and treatment options in oral verrucous carcinoma and discusses the existing dilemmas linked to this unique malignancy.
conclusionsOral verrucous carcinoma must be differentiated from conventional squamous cell carcinoma due to its less aggressive behaviour with a more favourable prognosis. Close communication between clinician and pathologist is mandatory for making a correct diagnosis. Primary surgery with negative surgical margins seems to be the most successful treatment. However, management recommendations are not uniform since they are mostly based on case reports and small retrospective case series. Prospective and pooled multi-institutional studies are therefore needed.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.