ArticleJournal of the American Heart Association2023
Cerebral and Retinal Infarction in Bicuspid Aortic Valve.
Article in Journal of the American Heart Association, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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4 citing papers in PubMed, 6 citations in OpenAlex.
- Chromosomal Location and Identification ofDiagnostics (Basel, Switzerland) · 2025Article
- Clinical impact of cardiovascular calcifications on stroke incidence in primary prevention: analysis in NADESICO study.Heart and vessels · 2024Article
- Bicuspid Aortic Valve, from the Unknown till the Perfection of the Species.Reviews in cardiovascular medicine · 2024Review
- Spontaneous calcified cerebral emboli: a comprehensive review and proposed diagnostic criteria.Frontiers in neurology · 2024Review
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Authors and funding
10 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background Description of cerebral and retinal infarction in patients with bicuspid aortic valve (BAV) is limited to case reports. We aimed to characterize cerebral and retinal infarction and examine outcomes in patients with BAV. Methods and Results Consecutive patients from 1975 to 2015 with BAV (n=5401) were retrospectively identified from the institutional database; those with confirmed cerebral or retinal infarction were analyzed. Infarction occurring after aortic valve replacement was not included. Patients were grouped according to infarction pathogenesis: embolism from a degenerative calcific BAV (BAVi); non-BAV, large artery atherosclerotic or lacunar infarction (LAi); and non-BAV, non-large artery embolic infarction (nLAi). There were 83/5401 (1.5%) patients, mean age 54±12 years and 28% female, with confirmed cerebral or retinal infarction (LAi 23/83 [28%]; nLAi 30/83 [36%]; BAVi 26/83 [31%]; other 4/83 [5%]). Infarction was embolic in 72/83 (87%), and 35/72 (49%) were cardioembolic. CHA
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