ArticleCNS neuroscience & therapeutics2023
Speech and gait abnormalities in motor subtypes of de-novo Parkinson's disease.
Article in CNS neuroscience & therapeutics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Novel Insights Into the Causal Effects and Shared Genetics Between Body Fat and Parkinson Disease.CNS neuroscience & therapeutics · 2024Pooled it
- A Machine Learning Approach to Voice-Based Parkinson Disease Screening Using Multiview Spectrogram and Speech Recognition Features: Diagnostic Study.JMIR medical informatics · 2026Article
- Pauses as a Quantitative Measure of Linguistic Planning Challenges in Parkinson's Disease.Brain sciences · 2025Article
- Prediction of Parkinson Disease Using Long-Term, Short-Term Acoustic Features Based on Machine Learning.Brain sciences · 2025Article
- Speech and language biomarkers for Parkinson's disease prediction, early diagnosis and progression.NPJ Parkinson's disease · 2025Review
- Automated analysis of spoken language differentiates multiple system atrophy from Parkinson's disease.Journal of neurology · 2025Article
- The comparison of gait disorders among different motor subtypes in Parkinson's disease patients during the early and middle stages.Clinical parkinsonism & related disorders · 2025Article
- Speech subtypes are associated with worsened tremor and axial symptoms in Parkinson's disease patients.Clinical parkinsonism & related disorders · 2025Article
- "Does speech in patients with different Parkinson's disease subtypes decline over time?"Clinical parkinsonism & related disorders · 2025Article
- Effects of different side motor impairments at early onset on voice acoustic performance in patients with Parkinson's disease.Clinical parkinsonism & related disorders · 2025Article
- Is self-perception related to speech perceptual analysis measures in early- and late-onset Parkinson's disease?Dementia & neuropsychologia · 2025Article
- Balance and gait disorders in de novo Parkinson's disease: support for early rehabilitation.Journal of neurology · 2024Article
- Acoustic assessment in mandarin-speaking Parkinson's disease patients and disease progression monitoring and brain impairment within the speech subsystem.NPJ Parkinson's disease · 2024Review
- Effects of Deep-Brain Stimulation on Speech: Perceptual and Acoustic Data.Journal of speech, language, and hearing research : JSLHR · 2024Article
- Speech and gait abnormalities in motor subtypes of de-novo Parkinson's disease.CNS neuroscience & therapeutics · 2023Article
- Speech Characteristics Across Motor Subtypes of Parkinson's Disease.International journal of language & communication disordersArticle
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo investigate the presence and relationship of temporal speech and gait parameters in patients with postural instability/gait disorder (PIGD) and tremor-dominant (TD) motor subtypes of Parkinson's disease (PD).
methodsSpeech samples and instrumented walkway system assessments were acquired from a total of 60 de-novo PD patients (40 in TD and 20 in PIGD subtype) and 40 matched healthy controls. Objective acoustic vocal assessment of seven distinct speech timing dimensions was related to instrumental gait measures including velocity, cadence, and stride length.
resultsCompared to controls, PIGD subtype showed greater consonant timing abnormalities by prolonged voice onset time (VOT) while also shorter stride length during both normal walking and dual task, while decreased velocity and cadence only during dual task. Speaking rate was faster in PIGD than TD subtype. In PIGD subtype, prolonged VOT correlated with slower gait velocity (r = -0.56, p = 0.01) and shorter stride length (r = -0.59, p = 0.008) during normal walking, whereas relationships were also found between decreased cadence in dual task and irregular alternating motion rates (r = -0.48, p = 0.04) and prolonged pauses (r = -0.50, p = 0.03). No correlation between speech and gait was detected in TD subtype.
conclusionOur findings suggest that speech and gait rhythm disorder share similar underlying pathomechanisms specific for PIGD subtype.
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