Evidence map›Paper›PMID 36942501›Full record

ArticleCNS neuroscience & therapeutics2023

Functional recovery continues beyond 3 months post-basilar artery thrombectomy: A retrospective cohort study.

Lakshini Gunasekera, Peter Mitchell, Richard J Dowling, Steven Bush, Bernard Yan

Abstract read
In one paragraph

Article in CNS neuroscience & therapeutics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Lakshini GunasekeraMelbourne Brain Centre at Royal Melbourne Hospital, University of Melbourne, Parkville, Melbourne, Victoria, Australia.ORCID 0000-0002-2292-8155
Peter MitchellNeurointervention Service, Department of Radiology, Royal Melbourne Hospital, Melbourne, Victoria, Australia.
Richard J DowlingNeurointervention Service, Department of Radiology, Royal Melbourne Hospital, Melbourne, Victoria, Australia.
Steven BushNeurointervention Service, Department of Radiology, Royal Melbourne Hospital, Melbourne, Victoria, Australia.
Bernard YanMelbourne Brain Centre at Royal Melbourne Hospital, University of Melbourne, Parkville, Melbourne, Victoria, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionUntreated basilar artery occlusion (BAO) carries 70% mortality. Guidelines recommend thrombectomy with or without thrombolysis.

aimWe compared Modified Rankin Scores (mRS) at 3 and 12 months post thrombectomy to determine benefit of long-term follow up.

methodsRetrospective, single centre analysis of BAO thrombectomies between 2015 and 2019. Inclusion criteria were symptomatic BAO on CT angiography, absent early ischemic changes, premorbid independence and intervention within 24 h. All received stroke ward care. Results were analysed with simple statistics and binary logistic regression as appropriate.

resultsOf 82 patients: most were male (61%, 50/82) with median age 68 years (IQR 17 years) and median NIHSS 14 (IQR 15). Median door-to-puncture time was 42 min (IQR 72 min). Total deaths were 34.1% (28/82) at 3 months, and 37.8% (31/82) at 12 months. Of 51 patients alive at 12 months: 41% (21/51) had improved mRS, 16% (8/51) had worse mRS and 43% (22/51) had unchanged mRS, compared to 3 months. Improvements to mRS were: one point in 57.1% (14/21), two points in 28.9% (6/21) and three points in 4.8% (1/21). Nursing home admission was avoided in 11.8% (6/51) who improved from mRS4. Increased age was associated with decreased likelihood of reaching the primary outcome OR 0.87, 95% CI 0.76-0.99 (p value = 0.03).

conclusionOver a quarter of patients improved beyond 3 months. Future studies should adopt long-term follow up as primary outcome.

Indexed as

Endovascular ProceduresStrokeVertebrobasilar InsufficiencyAgedBasilar ArteryFemaleHumansMaleRetrospective StudiesThrombectomyTreatment Outcomebasilar artery occlusionmodified Rankin scorestrokethrombectomy

Identifiers

PMID36942501
PMCPMC10352879

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.