Evidence map›Paper›PMID 36942311›Full record

ArticleMaterials today. Bio2023

Exosomes incorporated with black phosphorus quantum dots attenuate retinal angiogenesis via disrupting glucose metabolism.

Xiao Gui, Haorui Zhang, Rui Zhang, Qing Li, Weiye Zhu, Zheng Nie, Jiawei Zhao, Xiao Cui, Weiju Hao, Xudong Wen and 2 more

Open access · goldAbstract read
In one paragraph

Article in Materials today. Bio, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
3.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 24 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Xiao GuiDepartment of Ophthalmology, Shanghai Changhai Hospital, No. 168 Changhai Road, Shanghai, 200433, China.
Haorui ZhangDepartment of Ophthalmology, Shanghai Changhai Hospital, No. 168 Changhai Road, Shanghai, 200433, China.
Rui ZhangDepartment of Ophthalmology, Shanghai Changhai Hospital, No. 168 Changhai Road, Shanghai, 200433, China.
Qing LiDepartment of Ophthalmology, Shanghai Changhai Hospital, No. 168 Changhai Road, Shanghai, 200433, China.
Weiye ZhuDepartment of Ophthalmology, Shanghai Changhai Hospital, No. 168 Changhai Road, Shanghai, 200433, China.
Zheng NieDepartment of Ophthalmology, Shanghai Changhai Hospital, No. 168 Changhai Road, Shanghai, 200433, China.
Jiawei ZhaoDepartment of Ophthalmology, Shanghai Changhai Hospital, No. 168 Changhai Road, Shanghai, 200433, China.
Xiao CuiDepartment of Ophthalmology, Shanghai Changhai Hospital, No. 168 Changhai Road, Shanghai, 200433, China.
Weiju HaoUniversity of Shanghai for Science and Technology, Shanghai, 200093, PR China.
Xudong WenDepartment of Gastroenterology, Chengdu Integrated TCM&Western Medicine Hospital, Chengdu University of TCM, Chengdu, 610016, China.
Wei ShenDepartment of Ophthalmology, Shanghai Changhai Hospital, No. 168 Changhai Road, Shanghai, 200433, China.
Hongyuan SongDepartment of Ophthalmology, Shanghai Changhai Hospital, No. 168 Changhai Road, Shanghai, 200433, China.
Second Military Medical University · CNChengdu University · CNUniversity of Shanghai for Science and Technology · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Black phosphorus quantum dots (BPQDs) have shown potential in tumor therapy, however, their anti-angiogenic functions have not been studied. Although BPQDs are easily degraded to non-toxic phosphrous, the reported toxicity, poor stability, and non-selectivity largely limit their further application in medicine. In this study, a vascular targeting, biocompatible, and cell metabolism-disrupting nanoplatform is engineered by incorporating BPQDs into exosomes modified with the Arg-Gly-Asp (RGD) peptide (BPQDs@RGD-EXO nanospheres, BREs). BREs inhibit endothelial cells (ECs) proliferation, migration, tube formation, and sprouting

Indexed as

AngiogenesisBlack phosphorus quantum dotsCell metabolismExosomesRetinopathy

Identifiers

PMID36942311
PMCPMC10024194
OpenAlexW4323030727

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.