Evidence map›Paper›PMID 36942276›Full record

ArticleSaudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society2023

Patients' and primary carers' views on clozapine treatment for schizophrenia: A cross-sectional study in Qatar.

Ahmad Srour, Yassin Eltorki, Humayun Malik, Majid A Alabdulla, Mohamed H M O Hassan, Maha Ahmed Al Subaiey, Peter Michael Haddad

Open access · hybridAbstract read
In one paragraph

Article in Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Ahmad SrourDepartment of Psychiatry, Hamad Medical Corporation, Qatar.
Yassin EltorkiDepartment of Psychiatry, Hamad Medical Corporation, Qatar.
Humayun MalikDepartment of Psychiatry, Hamad Medical Corporation, Qatar.
Majid A AlabdullaDepartment of Psychiatry, Hamad Medical Corporation, Qatar.
Mohamed H M O HassanDepartment of Psychiatry, Hamad Medical Corporation, Qatar.
Maha Ahmed Al SubaieyDepartment of Psychiatry, Hamad Medical Corporation, Qatar.
Peter Michael HaddadDepartment of Psychiatry, Hamad Medical Corporation, Qatar.
Hamad Medical Corporation · QAManchester Academic Health Science Centre · GBQatar University · QA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Subjective views of clozapine treatment among patients with schizophrenia in the Middle East and North African MENA Region have not previously been assessed. Globally, few studies have assessed the views of carers to clozapine treatment. We conducted a cross-sectional survey, using a clinician administered structured interview, of patients with schizophrenia/schizoaffective disorder prescribed clozapine in Qatar, and their primary carers. Participants were asked to rate clozapine against prior their antipsychotic treatment in terms of specific benefits and side effects. Forty-two patients and 33 carers participated in the study. Of the patients, two thirds were male, approximately half were Qatari and the mean age was 33.9 years. Patients and carers rated clozapine as superior to prior antipsychotic treatment on all 7 potential benefits inquired about. The greatest perceived benefit was improved mood. Patients rated clozapine as less likely to cause extrapyramidal side effects but more likely to cause 18 other potential side effects compared to prior antipsychotic treatment, with the greatest difference being for nocturnal salivation, increased appetite, and constipation

Indexed as

ClozapineGASS, Glasgow Antipsychotic Side-effects ScaleHMC, Hamad Medical CorporationIRB, Institutional Review BoardMENA, Middle East and North AfricaMRC, Medical Research CenterNNH, Number Needed to HarmQatarRCTs, Randomised Controlled TrialsSchizophreniaSide effectsSubjective experienceWCC, White Cell Count

Identifiers

PMID36942276
PMCPMC10023528
OpenAlexW4312193450

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.