Evidence map›Paper›PMID 36941924›Full record

ArticlePalliative medicine reports2023

Outcome of Surgery as Part of Palliative Care of Patients with Symptomatic Advanced or Metastatic Extra-Abdominal High-Grade Soft Tissue Sarcoma.

Farhad Farzaliyev, Hans-Ulrich Steinau, Andrej Ring, Rainer Hamacher, Tobias Thiel, Henrik Lauer, Lars Erik Podleska

Open access · goldFull text read
In one paragraph

Article in Palliative medicine reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Farhad FarzaliyevDepartment of Hand, Plastic, Reconstructive and Burn Surgery, BG Klinik, Eberhard Karls University, Tuebingen, Germany.ORCID https://orcid.org/0000-0002-4727-5699
Hans-Ulrich SteinauDepartment of Tumor Orthopedics and Sarcoma Surgery, University Hospital Essen, Essen, Germany.
Andrej RingDepartment of Plastic and Reconstructive Surgery, St. Rochus Hospital, Castrop-Rauxel, Germany.
Rainer HamacherDepartment of Medical Oncology, Sarcoma Center, West German Cancer Center, University Hospital Essen, Essen, Germany.
Tobias ThielDepartment of Hand, Plastic, Reconstructive and Burn Surgery, BG Klinik, Eberhard Karls University, Tuebingen, Germany.
Henrik LauerDepartment of Hand, Plastic, Reconstructive and Burn Surgery, BG Klinik, Eberhard Karls University, Tuebingen, Germany.
Lars Erik PodleskaDepartment of Tumor Orthopedics and Sarcoma Surgery, University Hospital Essen, Essen, Germany.
BG Klinik Tübingen · DEEssen University Hospital · DERütgers (Germany) · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The modern multimodal treatment of malignant tumors has increased disease-specific survival and decreased the burden of tumor-associated complications. The main focus of palliative surgery is not based primarily on quantitative success parameters of tumor response but is instead mainly on the question of quality of life. Aim: The current study was conducted to analyze the clinical and oncological outcomes of palliative patients with soft tissue sarcoma. Design: Of 309 patients with extra-abdominal high-grade soft tissue sarcoma treated between August 2012 and December 2014, our retrospective analysis revealed 33 palliative patients for this study. All patients were evaluated and managed by a multidisciplinary team with expertise and experience in sarcoma treatment. The survival analysis was made using the Kaplan-Meier method. Results: The main sarcoma symptoms were pain (27.3%) and ulcerated tumors or shortly before ulceration (24.2%). Thirteen patients (39.4%) were operated on with negative margins, 15 (45.5%) with positive margins, 2 with tumor debulking (6.1%), and 3 patients (9.1%) were treated only with palliative hyperthermic isolated limb perfusion. Ten pedicle flaps were performed after sarcoma resection. The median operation time was 85 minutes (range, 37-216 minutes). The median hospitalization stay was 9.5 days (range, 3-27 days). No patients died during hospitalization. Twelve-month disease-free survival was 48.5% (95% confidence interval: 45.4-51.6). Conclusions: Palliative surgery of metastatic or advanced soft tissue sarcoma can improve the wound care and quality of life. Closed noninfected wounds enable further treatment options, such as chemotherapy, immunotherapy, and radiotherapy. This surgery should be considered during the discussion on interdisciplinary tumor boards.

Indexed as

advanced soft tissue sarcomapalliative plastic surgeryretrospective studysarcoma resection

Identifiers

PMID36941924
PMCPMC10024585
OpenAlexW4327720829

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Textfull text, public
LicenceCC BY
measurements read25
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.