Evidence map›Paper›PMID 36941514›Full record

ArticleMolecular imaging and biology2023

2-deoxy-2-[

Philip Z Mannes, Clayton E Barnes, Joseph D Latoche, Kathryn E Day, Jessie R Nedrow, Janet S Lee, Sina Tavakoli

Open access · bronzeAbstract read
In one paragraph

Article in Molecular imaging and biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Philip Z MannesDepartment of Radiology, University of Pittsburgh, Pittsburgh, PA, USA.
Clayton E BarnesDepartment of Radiology, University of Pittsburgh, Pittsburgh, PA, USA.
Joseph D LatocheDepartment of Medicine, University of Pittsburgh, Pittsburgh, PA, USA.
Kathryn E DayDepartment of Medicine, University of Pittsburgh, Pittsburgh, PA, USA.
Jessie R NedrowDepartment of Radiology, University of Pittsburgh, Pittsburgh, PA, USA.
Janet S LeeDivision of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, University of Pittsburgh, Pittsburgh, PA, USA.
Sina TavakoliDepartment of Radiology, University of Pittsburgh, Pittsburgh, PA, USA. sit23@pitt.edu.ORCID 0000-0003-0574-3914
University of Pittsburgh · US

Funding

VECTOR CORE FACILITYP30CA047904 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Jessie Nedrow · 1988 to 2026
$158.0M
Regulation of Cardiolin Byosynthesis in Epithelial InjuryP01HL114453 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI KAGAN, VALERIAN E · 2014 to 2023
$21.3M
Mechanisms of host protection against pathogen-secreted proteases in acute lung injuryR01HL136143 · NHLBI · WASHINGTON UNIVERSITY · PI LEE, JANET SOJUNG · 2017 to 2024
$4.4M
The role of ACOD1 in immunomodulation in intrapulmonary Klebsiella pneumoniae infectionR01HL142084 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI CHEN, KONG · 2018 to 2021
$2.4M
A Molecular Imaging Approach to Immuno-Metabolic Characterization of Vessel Wall MacrophagesK08HL144911 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI TAVAKOLI, SINA · 2019 to 2023
$813k
Novel Protease-Activatable Tracers for Targeted Imaging of Chemerin Receptor in InflammationR21EB027871 · NIBIB · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI TAVAKOLI, SINA · 2020 to 2022
$626k
Patient-Oriented Research in Acute Lung Injury and Host Defense in the ICUK24HL143285 · NHLBI · WASHINGTON UNIVERSITY · PI LEE, JANET SOJUNG · 2019 to 2023
$579k
Molecular Imaging of the ChemR23-Chemerin Axis in Acute Lung InjuryF30HL158038 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI MANNES, PHILIP ZACHARY · 2021 to 2024
$209k
NCI NIH HHS P30 CA047904NHLBI NIH HHS F30 HL158038NHLBI NIH HHS K08 HL144911NHLBI NIH HHS K24 HL143285NHLBI NIH HHS P01 HL114453NHLBI NIH HHS R01 HL136143NHLBI NIH HHS R01 HL142084NIBIB NIH HHS R21 EB027871
6 · The paper itself

Abstract

purposeTo image inflammation and monitor therapeutic response to anti-inflammatory intervention using 2-deoxy-2-[ PROCEDURES: Mice were intratracheally administered lipopolysaccharide (LPS, 2.5 mg/kg) to induce ALI or phosphate-buffered saline as the vehicle control. A subset of mice in the ALI group received two intraperitoneal doses of dexamethasone 1 and 24 h after LPS. [

resultsLung uptake of [

conclusions[

Indexed as

Acute Lung InjuryPneumoniaAnimalsDexamethasoneDisease Models, AnimalFluorodeoxyglucose F18GlucoseLeukocyte ElastaseLipopolysaccharidesMicePositron-Emission TomographyPositron Emission Tomography Computed TomographyDexamethasoneFluorodeoxyglucose F18GlucoseLeukocyte ElastaseLipopolysaccharides[18F]FDGAcute lung injuryInflammationPositron emission tomography

Identifiers

PMID36941514
PMCPMC10027262
OpenAlexW4327910527

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.