Evidence map›Paper›PMID 36941485›Full record

ArticleEuropean geriatric medicine2023

Characteristics and clinical outcomes of acute cholangitis in older patients.

Fatih Acehan, Hüseyin Çamlı, Cagdas Kalkan, Mesut Tez, Emin Altiparmak, Ihsan Ates

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Article in European geriatric medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

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6citing papers in PubMed
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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

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3 · Its place in the literature

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6 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Fatih AcehanDepartment of Internal Medicine, Ankara City Hospital, Universiteler Neighborhood, 1604. Street No: 9 Çankaya, 06800, Ankara, Turkey. acehanf@gmail.com.ORCID http://orcid.org/0000-0001-8469-0907
Hüseyin ÇamlıDepartment of Internal Medicine, Ankara City Hospital, Universiteler Neighborhood, 1604. Street No: 9 Çankaya, 06800, Ankara, Turkey.
Cagdas KalkanDepartment of Gastroenterology, Ankara City Hospital, Ankara, Turkey.
Mesut TezDepartment of General Surgery, Ankara City Hospital, Ankara, Turkey.
Emin AltiparmakDepartment of Gastroenterology, Ankara City Hospital, Ankara, Turkey.
Ihsan AtesDepartment of Internal Medicine, Ankara City Hospital, Universiteler Neighborhood, 1604. Street No: 9 Çankaya, 06800, Ankara, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeFew studies are available on older patients with acute cholangitis. In this study, we aimed to examine the clinical characteristics of older patients with acute cholangitis.

methodsPatients aged 65 years and over who were diagnosed with acute cholangitis between February 2019 and August 2022 were analyzed retrospectively. Patients eligible for the study were divided into two groups as those aged ≥ 80 years (octogenarian) and those aged 65-79 years (non-octogenarian). These two groups were then compared for many clinical characteristics. In addition, factors associated with in-hospital mortality were identified. Finally, a subgroup analysis was performed in patients with non-malignant etiology.

resultsOf a total of 309 enrolled patients, 120 (38.8%) were in the octogenarian group and 189 (61.2%) were in the non-octogenarian group. The mean age was 77.2 ± 8.0 years and 51.8% were women. Severe disease and intensive care unit admission rates were higher in the octogenarian group (p = 0.035 and p = 0.002, respectively), but there was no significant difference in the rate of in-hospital mortality (p = 0.146). Malignant etiology (OR 2.990, 95% CI 1.131-7.904) and hypoalbuminemia (OR 0.824, 95% CI 0.751-0.903) were independent risk factors for in-hospital mortality. In the subgroup analysis of non-malignant etiology, the octogenarian group had a significantly higher in-hospital mortality rate than the non-octogenarian group (8.8% vs. 3.2%, p = 0.048).

conclusionsAmong older patients with acute cholangitis, clinicians should closely monitor those aged 80 years and over, as well as those with malignant etiology and hypoalbuminemia, due to their high risk of serious clinical events.

Indexed as

CholangitisHypoalbuminemiaAcute DiseaseAgedAged, 80 and overCholangiopancreatography, Endoscopic RetrogradeFemaleHumansMaleRetrospective StudiesTurkeyAcute cholangitisHypoalbuminemiaIn-hospital mortalityMalignant biliary obstructionOctogenarianOlder patients

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PMID36941485

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.