Evidence map›Paper›PMID 36941401›Full record

ArticleInsights into imaging2023

Prognostic significance of non-infarcted myocardium correlated with microvascular impairment evaluated dynamically by native T1 mapping.

Bing-Hua Chen, Dong-Aolei An, Chong-Wen Wu, Ting Yue, Matthew Bautista, Erika Ouchi, Jian-Rong Xu, Jiani Hu, Yan Zhou, Jun Pu and 1 more

Full text read
PubMed Full text at PMC Publisher
In one paragraph

Article in Insights into imaging, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Bing-Hua Chen *Department of Radiology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, No.160 PuJian Road, Shanghai, 200127, P. R. China.
Dong-Aolei An *Department of Radiology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, No.160 PuJian Road, Shanghai, 200127, P. R. China.
Chong-Wen Wu *Department of Radiology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, No.160 PuJian Road, Shanghai, 200127, P. R. China.
Ting YueDepartment of Radiology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, No.160 PuJian Road, Shanghai, 200127, P. R. China.
Matthew BautistaDepartment of Radiology, Wayne State University, Detroit, MI, 48201, USA.
Erika OuchiDepartment of Radiology, Wayne State University, Detroit, MI, 48201, USA.
Jian-Rong XuDepartment of Radiology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, No.160 PuJian Road, Shanghai, 200127, P. R. China.
Jiani HuDepartment of Radiology, Wayne State University, Detroit, MI, 48201, USA.
Yan Zhou *Department of Radiology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, No.160 PuJian Road, Shanghai, 200127, P. R. China. zhouyan@renji.com.
Jun Pu *Department of Cardiology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, No.160 PuJian Road, Shanghai, 200127, P. R. China. 9150@renji.com.
Lian-Ming Wu *Department of Radiology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, No.160 PuJian Road, Shanghai, 200127, P. R. China. wlmssmu@126.com.

Funding

National Natural Science Foundation of China 81873886National Natural Science Foundation of China 81873887National Natural Science Foundation of China 82171884National Outstanding Youth Science Fund Project of National Natural Science Foundation of China 82101981Shanghai Jiao Tong University medical engineering cross project YG2022QN016Shanghai Municipal Education Commission-Gao feng Clinical Medicine Grant: Shanghai Jiao Tong University school of medicine Double hundred outstanding person project 20191904Shanghai Science and technology innovation action plan, technology standard project Grant numbers 19DZ2203800
6 · The paper itself

Abstract

objectivesThis study aimed to investigate the influence of microvascular impairment on myocardial characteristic alterations in remote myocardium at multiple time points, and its prognostic significance after acute ST-segment elevation myocardial infarction (STEMI).

methodsPatients were enrolled prospectively and performed CMR at baseline, 30 days, and 6 months. The primary endpoint was major adverse cardiac events (MACE): death, myocardial reinfarction, malignant arrhythmia, and hospitalization for heart failure. Cox proportional hazards regression modeling was analyzed to estimate the correlation between T1 mapping of remote myocardium and MACE in patients with and without microvascular obstruction (MVO).

resultsA total of 135 patients (mean age 60.72 years; 12.70% female, median follow-up 510 days) were included, of whom 86 (63.70%) had MVO and 26 (19.26%) with MACE occurred in patients. Native T1 values of remote myocardium changed dynamically. At 1 week and 30 days, T1 values of remote myocardium in the group with MVO were higher than those without MVO (p = 0.030 and p = 0.001, respectively). In multivariable cox regression analysis of 135 patients, native

conclusionsThe evolution of native T1 in remote myocardium was associated with the extent of microvascular impairment after reperfusion injury. In patients with MVO, native

Indexed as

FibrosisMagnetic resonance imagingMyocardial infarctionT1 mappingVentricular remodeling

Identifiers

PMID36941401
PMCPMC10027971

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read103
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.