Evidence map›Paper›PMID 36941364›Full record

ArticleNeuropsychopharmacology : official publication of the American College of Neuropsychopharmacology2023

BNST PKCδ neurons are activated by specific aversive conditions to promote anxiety-like behavior.

Kellie M Williford, Anne Taylor, James R Melchior, Hye Jean Yoon, Eryn Sale, Milen D Negasi, Danielle N Adank, Jordan A Brown, Michelle N Bedenbaugh, Joseph R Luchsinger and 5 more

Open access · greenAbstract read
In one paragraph

Article in Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
11.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 35 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. A Distinct Subpopulation of Extended Amygdala Neurons Drives Food Intake.Biological psychiatry global open science · 2026
    Article
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  8. Dorsal Raphe VIP Neurons Are Critical for Survival-Oriented Vigilance.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  9. Article
  10. Sex-specific relationships between stress coping and avoidance behavior.bioRxiv : the preprint server for biology · 2026
    Article
  11. Article
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  14. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 1 institution in 1 country.

Kellie M WillifordVanderbilt Brain Institute, Vanderbilt University, Nashville, TN, USA.ORCID http://orcid.org/0000-0002-7405-6459
Anne TaylorVanderbilt Brain Institute, Vanderbilt University, Nashville, TN, USA.
James R MelchiorVanderbilt Center for Addiction Research, Vanderbilt University, Nashville, TN, USA.
Hye Jean YoonVanderbilt Center for Addiction Research, Vanderbilt University, Nashville, TN, USA.ORCID http://orcid.org/0000-0002-3830-3678
Eryn SaleVanderbilt Center for Addiction Research, Vanderbilt University, Nashville, TN, USA.
Milen D NegasiVanderbilt Center for Addiction Research, Vanderbilt University, Nashville, TN, USA.
Danielle N AdankVanderbilt Brain Institute, Vanderbilt University, Nashville, TN, USA.ORCID http://orcid.org/0000-0002-8206-6702
Jordan A BrownVanderbilt Center for Addiction Research, Vanderbilt University, Nashville, TN, USA.
Michelle N BedenbaughVanderbilt Center for Addiction Research, Vanderbilt University, Nashville, TN, USA.
Joseph R LuchsingerVanderbilt Brain Institute, Vanderbilt University, Nashville, TN, USA.
Samuel W CentanniVanderbilt Brain Institute, Vanderbilt University, Nashville, TN, USA.ORCID http://orcid.org/0000-0002-3941-7677
Sachin PatelVanderbilt Brain Institute, Vanderbilt University, Nashville, TN, USA.ORCID http://orcid.org/0000-0001-8052-520X
Erin S CalipariVanderbilt Brain Institute, Vanderbilt University, Nashville, TN, USA.ORCID http://orcid.org/0000-0003-4723-0623
Richard B SimerlyVanderbilt Brain Institute, Vanderbilt University, Nashville, TN, USA.
Danny G WinderVanderbilt Brain Institute, Vanderbilt University, Nashville, TN, USA. danny.winder@vanderbilt.edu.ORCID http://orcid.org/0000-0002-6185-4769
Vanderbilt University · US

Funding

Overall: Eunice Kennedy Shriver Intellectual and Developmental Disabilities Research Center at VanderbiltP50HD103537 · NICHD · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Lea K Davis · 2020 to 2026
$10.3M
Sex Dependent Recruitment of PKCdelta Neurons by Stress: Administrative Supplement for Noradrenergic Regulation in the BNSTR01DA042475 · NIDA · VANDERBILT UNIVERSITY · PI WINDER, DANNY G. · 2016 to 2025
$4.0M
BNST PKCdelta Roles in Affective BehaviorF99NS120599 · NINDS · VANDERBILT UNIVERSITY · PI WILLIFORD, KELLIE M · 2020 to 2021
$63k
NICHD NIH HHS P50 HD103537NIDA NIH HHS R01 DA042475NINDS NIH HHS F99 NS120599
6 · The paper itself

Abstract

The bed nucleus of the stria terminalis (BNST) is a critical mediator of stress responses and anxiety-like behaviors. Neurons expressing protein kinase C delta (BNST

Indexed as

Central Amygdaloid NucleusSeptal NucleiAffectAnxietyNeurons

Identifiers

PMID36941364
PMCPMC10209190
OpenAlexW4327938851

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.