ArticleSaudi medical journal2023
The characteristics of Grave's disease in children and adolescent patients in Al-Madinah Al-Munawwarah: A retrospective chart review.
Article in Saudi medical journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed, 3 citations in OpenAlex.
- Clinical Pattern of Graves' Disease and Management Preferences Among Pediatric Endocrinologists in Saudi Arabia, A Decade of Experience.Clinical medicine insights. Endocrinology and diabetes · 2026Article
- Refractory Graves' Disease in an Adolescent Successfully Treated With Cholestyramine and Subsequent Thyroidectomy.Cureus · 2024Article
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9 authors at 1 institution in 1 country.
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Abstract
objectivesTo determine the characteristics of Graves' disease in children and adolescents in Medina, the Kingdom of Saudi Arabia, and compare them to those observed in other countries.
methodsThis is a retrospective chart review of children and adolescents diagnosed with Graves' disease between January 2010 and May 2021.
resultsFifty-eight patients aged 12.02 ± 4.85 years were identified, of which 44 (75.9%) were females. Exophthalmos (63.8%), neck swelling (60.3%), palpitations (46.6%), and tremors (29.3%) were the most common manifestations. Vitiligo (1.72%) and alopecia (1.72%) were the only autoimmune diseases observed in our patients. The median (IQR) value was 0.01 (0.36) (ulU/mL) for thyroid-stimulating hormone (TSH) and 24.89 (29.50) (pmol/L) for FT4. In terms of treatment modalities, 55 (94.8%) received antithyroid medication, 6 (10.3%) underwent thyroidectomy and one patient (1.72%) was treated with radioactive iodine.
conclusionIn general, Graves' disease is more common in females. Neck swelling, palpitation, and tremors were the main manifestations. Compared with other countries, there was a higher frequency of exophthalmos and a lower frequency of associated autoimmune conditions. The primary treatment was antithyroid drugs; thyroidectomy and radioactive iodine were used less frequently.
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