Evidence map›Paper›PMID 36940959›Full record

ArticleSaudi medical journal2023

Lena M Hassen, Maha H Daghestani, Mohammed A Omair, Arwa K Althomali, Fatimah B Almukaynizi, Ibrahim A Almaghlouth

Open access · diamondFull text read
In one paragraph

Article in Saudi medical journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 4 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Lena M HassenFrom the Department of Zoology (Hassen, Daghestani), College of Sciences; from the Department of Medicine (Hassen, Omair, Almaghlouth), Rheumatology Unit; from the College of Medicine Research Center (Almaghlouth), College of Medicine; and from Prince Naif for Health Research Center (Althomali, Almukaynizi), King Saud University, Riyadh, Kingdom of Saudi Arabia.
Maha H DaghestaniFrom the Department of Zoology (Hassen, Daghestani), College of Sciences; from the Department of Medicine (Hassen, Omair, Almaghlouth), Rheumatology Unit; from the College of Medicine Research Center (Almaghlouth), College of Medicine; and from Prince Naif for Health Research Center (Althomali, Almukaynizi), King Saud University, Riyadh, Kingdom of Saudi Arabia.
Mohammed A OmairFrom the Department of Zoology (Hassen, Daghestani), College of Sciences; from the Department of Medicine (Hassen, Omair, Almaghlouth), Rheumatology Unit; from the College of Medicine Research Center (Almaghlouth), College of Medicine; and from Prince Naif for Health Research Center (Althomali, Almukaynizi), King Saud University, Riyadh, Kingdom of Saudi Arabia.
Arwa K AlthomaliFrom the Department of Zoology (Hassen, Daghestani), College of Sciences; from the Department of Medicine (Hassen, Omair, Almaghlouth), Rheumatology Unit; from the College of Medicine Research Center (Almaghlouth), College of Medicine; and from Prince Naif for Health Research Center (Althomali, Almukaynizi), King Saud University, Riyadh, Kingdom of Saudi Arabia.
Fatimah B AlmukayniziFrom the Department of Zoology (Hassen, Daghestani), College of Sciences; from the Department of Medicine (Hassen, Omair, Almaghlouth), Rheumatology Unit; from the College of Medicine Research Center (Almaghlouth), College of Medicine; and from Prince Naif for Health Research Center (Althomali, Almukaynizi), King Saud University, Riyadh, Kingdom of Saudi Arabia.
Ibrahim A AlmaghlouthFrom the Department of Zoology (Hassen, Daghestani), College of Sciences; from the Department of Medicine (Hassen, Omair, Almaghlouth), Rheumatology Unit; from the College of Medicine Research Center (Almaghlouth), College of Medicine; and from Prince Naif for Health Research Center (Althomali, Almukaynizi), King Saud University, Riyadh, Kingdom of Saudi Arabia.
King Saud University · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo determine the prevalence of selected single nucleotide polymorphisms (rs1080985, rs28624811, rs1065852, rs28371725, and rs1135840) in

methodsThis cross-sectional study was carried out on adult Saudi patients at King Khalid University Hospital, Riyadh, Saudi Arabia. Patients with confirmed SLE based on the 2012 Systemic Lupus International Collaborating Clinics classification criteria were included in the study. Peripheral blood was collected for genomic deoxyribonucleic acid extraction and TaqMan

resultsThere were 107 participants included in this study. Overall, the most predominant (23.4%) recessive genotype was AA in rs28624811, and the least prevalent (1.9%) recessive genotype was TT in rs28371725. Moreover, the variant rs1080985 genotypes (GC or CC) were significantly associated with the presence of serositis manifestation (OR=3.15,

conclusionSystemic lupus erythematosus patients carrying

Indexed as

Cytochrome P-450 CYP2D6Lupus Erythematosus, SystemicAdultCase-Control StudiesCross-Sectional StudiesGene FrequencyGenetic Predisposition to DiseaseGenotypeHumansPolymorphism, Single NucleotideSaudi ArabiaCYP2D6 protein, humanCytochrome P-450 CYP2D6clinical featurescytochrome P450genotypinglupusrisk allele

Identifiers

PMID36940959
PMCPMC10043891
OpenAlexW4327940009

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read45
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.