Evidence map›Paper›PMID 36940778›Full record

Observational studyJournal of substance use and addiction treatment2023

Examining neurobehavioral differences that support success in recovery from alcohol and other substance use disorders.

Medha K Satyal, Julia C Basso, Hannah Wilding, Liqa N Athamneh, Warren K Bickel

Abstract readObservational Study
In one paragraph

Observational study in Journal of substance use and addiction treatment, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Medha K SatyalDepartment of Human Nutrition, Foods, and Exercise, Virginia Tech, VA, USA.
Julia C BassoDepartment of Human Nutrition, Foods, and Exercise, Virginia Tech, VA, USA; Fralin Biomedical Research Institute at VTC, VA, USA; School of Neuroscience, Virginia Tech, VA, USA.
Hannah WildingSchool of Neuroscience, Virginia Tech, VA, USA.
Liqa N AthamnehFralin Biomedical Research Institute at VTC, VA, USA.
Warren K BickelFralin Biomedical Research Institute at VTC, VA, USA. Electronic address: wkbickel@vtc.vt.edu.

Funding

The integrated Translational Health Research Institute of Virginia (iTHRIV): Using Data to Improve HealthUL1TR003015 · NCATS · UNIVERSITY OF VIRGINIA · PI BROWN, DONALD E, JOHNSTON, KAREN C. · 2019 to 2023
$20.3M
Institutional Career Development CoreKL2TR003016 · NCATS · UNIVERSITY OF VIRGINIA · PI PAPIN, JASON, WORRALL, BRADFORD B · 2019 to 2023
$3.9M
Testing Reinforcer Pathology: Mechanisms and Interventions to Change Alcohol ValuationR01AA027381 · NIAAA · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI LACONTE, STEPHEN M · 2019 to 2023
$3.5M
NCATS NIH HHS KL2 TR003016NCATS NIH HHS UL1 TR003015NIAAA NIH HHS R01 AA027381
6 · The paper itself

Abstract

objectiveSubstance use disorders (SUDs) are brain disorders associated with impairments resulting from the recurrent use of alcohol, drugs, or both. Though recovery is possible, SUDs are chronic, relapsing-remitting disorders, with estimates of SUD relapse at 40-60%. Currently, we know little about the mechanisms underlying successful recovery processes and whether substance-specific mechanisms exist. The current study sought to examine delay discounting (a measure of future valuation), executive skills, abstinence duration, and health behaviors in a population of individuals in recovery from alcohol, stimulants, opioids, and other substances.

methodsIn this observational study, we utilized a cohort of individuals (n = 238) from the International Quit and Recovery Registry, an online registry for those in recovery from SUDs around the world. We assessed delay discounting through a neurobehavioral task, and assessed abstinence duration, executive skills, and engagement in positive health behaviors through self-report measures.

resultsWe found that delay discounting, executive skills, and engagement in positive health behaviors were similar among individuals in recovery from different substances. Abstinence duration was associated with delay discounting and engagement in health behaviors. Additionally, executive skills and engagement in health behaviors were positively associated.

conclusionThese findings suggest that common behavioral mechanisms support recovery from misuse of various substances. As both delay discounting and executive skills are dependent upon executive brain centers, such as the prefrontal cortex, strategies that target executive functioning, such as episodic future thinking, meditation, or exercise, may be efficient strategies for optimizing recovery from SUDs.

Indexed as

Delay DiscountingSubstance-Related DisordersBrainEthanolExecutive FunctionHumansEthanolAbstinenceAlcoholDrugsExecutive functioningHealth behaviors

Identifiers

PMID36940778
PMCPMC10193587

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.