Evidence map›Paper›PMID 36940628›Full record

ArticleJournal of psychiatric research2023

Prevalence and correlates of lifetime suicide attempt in obsessive-compulsive disorder with major depression.

Jack Samuels, O Joseph Bienvenu, Janice Krasnow, Marco A Grados, Bernadette A Cullen, Fernando S Goes, Nicole C McLaughlin, Steven A Rasmussen, Abby J Fyer, James A Knowles and 8 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of psychiatric research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 6 institutions in 1 country.

Jack SamuelsDepartment of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, USA. Electronic address: jacks@jhmi.edu.
O Joseph BienvenuDepartment of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Janice KrasnowDepartment of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Marco A GradosDepartment of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Bernadette A CullenDepartment of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Fernando S GoesDepartment of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Nicole C McLaughlinDepartment of Psychiatry and Human Behavior, Brown Medical School, Butler Hospital, Providence, RI, USA.
Steven A RasmussenDepartment of Psychiatry and Human Behavior, Brown Medical School, Butler Hospital, Providence, RI, USA.
Abby J FyerDepartment of Psychiatry, College of Physicians, Surgeons at Columbia University and the New York State Psychiatric Institute, New York City, New York, USA.
James A KnowlesDepartment of Cell Biology, SUNY Downstate Medical Center College of Medicine, Brooklyn, NY, USA.
James T McCrackenDepartment of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, School of Medicine, Los Angeles, CA, USA.
Dan GellerDepartment of Psychiatry, Harvard Medical School, Boston, MA, USA.
Mark A RiddleDepartment of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
John PiacentiniDepartment of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, School of Medicine, Los Angeles, CA, USA.
S Evelyn StewartDepartment of Psychiatry, Faculty of Medicine, University of British Columbia, Vancouver, USA.
Benjamin D GreenbergDepartment of Psychiatry and Human Behavior, Brown Medical School, Butler Hospital, Providence, RI, USA.
Gerald NestadtDepartment of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Paul NestadtDepartment of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Johns Hopkins University · USProvidence College · USUniversity of California, Los Angeles · USHarvard University · USNew York State Psychiatric InstituteSUNY Downstate Health Sciences University · US

Funding

OCD Collaborative Genetics Association StudyR01MH071507 · NIMH · JOHNS HOPKINS UNIVERSITY · PI NESTADT, GERALD · 2007 to 2010
$6.5M
Obsessive-compulsive disorder (OCD) Collaborative Genetics Association StudyR01MH079489 · NIMH · MASSACHUSETTS GENERAL HOSPITAL · PI GELLER, DANIEL A · 2007 to 2010
$3.4M
OCD Collaborative Genetics Association StudyR01MH079488 · NIMH · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI FYER, ABBY J · 2007 to 2010
$906k
Obsessive-compulsive disorder (OCD) Collaborative Genetics Association StudyR01MH079494 · NIMH · UNIVERSITY OF SOUTHERN CALIFORNIA · PI KNOWLES, JAMES A · 2007 to 2011
$840k
OCD Collaborative Genetics Association StudyR01MH079487 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI MCCRACKEN, JAMES T. · 2007 to 2010
$797k
NIMH NIH HHS R01 MH071507NIMH NIH HHS R01 MH079487NIMH NIH HHS R01 MH079488NIMH NIH HHS R01 MH079489NIMH NIH HHS R01 MH079494
6 · The paper itself

Abstract

backgroundLittle is known about specific obsessive-compulsive clinical features associated with lifetime history of suicide attempt in individuals with obsessive-compulsive disorder (OCD) and major depression.

methodsThe study sample included 515 adults with OCD and a history of major depression. In exploratory analyses, we compared the distributions of demographic characteristics and clinical features in those with and without a history of attempted suicide and used logistic regression to evaluate the association between specific obsessive-compulsive clinical features and lifetime suicide attempt.

resultsSixty-four (12%) of the participants reported a lifetime history of suicide attempt. Those who had attempted suicide were more likely to report having experienced violent or horrific images (52% vs. 30%; p < 0.001). The odds of lifetime suicide attempt were more than twice as great in participants with versus without violent or horrific images (O.R. = 2.46, 95%, CI = 1.45-4.19; p < 0.001), even after adjustment for other risk correlates of attempted suicide, including alcohol dependence, post-traumatic stress disorder, parental conflict, excessive physical discipline, and number of episodes of depression. The association between violent or horrific images and attempted suicide was especially strong in men, 18-29 year olds, those with post-traumatic stress disorder, and those with particular childhood adversities.

conclusionsViolent or horrific images are strongly associated with lifetime suicide attempts in OCD-affected individuals with a history of major depression. Prospective clinical and epidemiological studies are needed to elucidate the basis of this relationship.

Indexed as

Major Depressive DisorderObsessive-Compulsive DisorderAdultChildComorbidityDepressionHumansMalePrevalenceProspective StudiesSuicide, AttemptedMajor depressionObsessive-compulsive disorderSuicide attemptViolent images

Identifiers

PMID36940628
PMCPMC10149608
OpenAlexW4321764451

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.