Evidence map›Paper›PMID 36940081›Full record

ArticleInternational journal of clinical pharmacy2023

Optimising adherence to secondary prevention medications following acute coronary syndrome utilising telehealth cardiology pharmacist clinics: a matched cohort study.

Adam C Livori, Derk Pol, Bianca Levkovich, Ernesto Oqueli

Open access · hybridFull text read
In one paragraph

Article in International journal of clinical pharmacy, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Adam C LivoriPharmacy Department, Grampians Health Ballarat, 1 Drummond St Nth, Ballarat, VIC, 3350, Australia. adam.livori1@monash.edu.ORCID http://orcid.org/0000-0002-5337-8061
Derk PolPharmacy Department, Grampians Health Ballarat, 1 Drummond St Nth, Ballarat, VIC, 3350, Australia.
Bianca LevkovichPharmacy Department, Grampians Health Ballarat, 1 Drummond St Nth, Ballarat, VIC, 3350, Australia.
Ernesto OqueliPharmacy Department, Grampians Health Ballarat, 1 Drummond St Nth, Ballarat, VIC, 3350, Australia.
Ballarat Health Services · AUDeakin University · AULatrobe Regional Hospital · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAdherence to secondary prevention medications following acute coronary syndromes (ACS) is a predictor of future major adverse cardiovascular events. Underutilisation of these medications is associated with higher risk of major adverse cardiovascular events globally.

aimTo explore the effects of a telehealth cardiology pharmacist clinic on patient adherence to secondary prevention medications in the 12 months following ACS.

methodRetrospective matched cohort study within a large regional health service comparing patient populations before and after implementation of pharmacist clinic with 12-month follow up. Patients who received percutaneous coronary intervention for ACS were consulted by the pharmacist at 1, 3- and 12-months. Matching criteria included age, sex, presence of left ventricular dysfunction and ACS type. Primary outcome was difference in adherence in adherence at 12 months post ACS. Secondary outcomes included major adverse cardiovascular events at 12 months and validation of self-reported adherence using medication possession ratios from pharmacy dispensing records.

resultsThere were 156 patients in this study (78 matched pairs). Analysis of adherence at 12 months demonstrated an absolute increase in adherence by 13% (31 vs. 44%, p = 0.038). Furthermore, sub-optimal medical therapy (less than 3 ACS medication groups at 12 months) reduced by 23% (31 vs. 8%, p = 0.004).

conclusionThis novel intervention significantly improved adherence to secondary prevention medications at 12 months, a demonstrated contributor to clinical outcomes. Primary and secondary outcomes in the intervention group were both statistically significant. Pharmacist-led follow up improves adherence and patient outcomes.

Indexed as

Acute Coronary SyndromeCardiologyTelemedicineCohort StudiesFollow-Up StudiesHumansMedication AdherencePharmacistsRetrospective StudiesSecondary PreventionAcute coronary syndromeCardiologyMedication adherencePercutaneous coronary interventionPharmacists

Identifiers

PMID36940081
PMCPMC10026199
OpenAlexW4327893769

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read37
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.