Evidence map›Paper›PMID 36940063›Full record

ArticlePhysical and engineering sciences in medicine2023

A Monte Carlo study on dose distribution of an orthovoltage radiation therapy system.

Toshie Iseri, Yoshinori Tanabe, Ryouta Onizuka, Yuri Torigoe, Hiro Horikirizono, Kazuhito Itamoto, Hiroshi Sunahara, Harumichi Itoh, Kenji Tani, Munekazu Nakaichi

Abstract read
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In one paragraph

Article in Physical and engineering sciences in medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.8field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Toshie IseriDepartment of Veterinary Radiology, Joint Faculty of Veterinary Medicine, Yamaguchi University, 1677-1 Yoshida, Yamaguchi-shi, Yamaguchi, Yamagishi, Japan. iseri@yamaguchi-u.ac.jp.ORCID http://orcid.org/0000-0003-0306-9639
Yoshinori TanabeGraduate School of Health Sciences, Okayama University, Okayama, Japan.
Ryouta OnizukaDepartment of Therapeutic Radiology, Yamaguchi University Hospital, Yamaguchi, Japan.
Yuri TorigoeDepartment of Veterinary Radiology, Joint Faculty of Veterinary Medicine, Yamaguchi University, 1677-1 Yoshida, Yamaguchi-shi, Yamaguchi, Yamagishi, Japan.
Hiro HorikirizonoDepartment of Veterinary Radiology, Joint Faculty of Veterinary Medicine, Yamaguchi University, 1677-1 Yoshida, Yamaguchi-shi, Yamaguchi, Yamagishi, Japan.
Kazuhito ItamotoAnimal medical center, Joint faculty of Veterinary Medicine, Yamaguchi University, Yamaguchi, Japan.
Hiroshi SunaharaDepartment of Veterinary Surgery, Joint faculty of Veterinary Medicine, Yamaguchi University, Yamaguchi, Japan.
Harumichi ItohAnimal medical center, Joint faculty of Veterinary Medicine, Yamaguchi University, Yamaguchi, Japan.
Kenji TaniDepartment of Veterinary Surgery, Joint faculty of Veterinary Medicine, Yamaguchi University, Yamaguchi, Japan.
Munekazu NakaichiDepartment of Veterinary Radiology, Joint Faculty of Veterinary Medicine, Yamaguchi University, 1677-1 Yoshida, Yamaguchi-shi, Yamaguchi, Yamagishi, Japan.
Yamaguchi University · JPOkayama University · JPYamaguchi University Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

It is important to plan radiotherapy treatment and establish optimal dose distribution to reduce the chances of side effects and injury. Because there are no commercially available tools for calculating dose distribution in orthovoltage radiotherapy in companion animals, we developed an algorithm to accomplish this and verified its characteristics using tumor disease cases. First, we used the Monte Carlo method to develop an algorithm to calculate the dose distribution of orthovoltage radiotherapy (280 kVp; MBR-320, Hitachi Medical Corporation, Tokyo, Japan) using BEAMnrc at our clinic. Using development of Monte Carlo method, dose distribution for tumor and normal organs were evaluated in brain tumors, squamous cell carcinomas of the head, and feline nasal lymphomas. In all cases of brain tumors, the mean dose delivered to the GTV ranged from 36.2 to 76.1% of the prescribed dose due to the decrease through the skull. In the nasal lymphoma in cats, the eyes with covered a 2 mm-thick lead plate, the respective average dose to the eyes was 71.8% and 89.9% less than that to the uncovered eyes. The findings may be useful for informed decision making in orthovoltage radiotherapy with more effective and targeted irradiation and data collection allowing detailed informed consent.

Indexed as

Brain NeoplasmsRadiotherapy Planning, Computer-AssistedAlgorithmsAnimalsCatsMonte Carlo MethodRadiotherapy DosageMonte Carlo methodOrgans at riskRadiation treatmentRadiotherapy dosage

Identifiers

PMID36940063
OpenAlexW4327898740

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.