Evidence map›Paper›PMID 36939915›Full record

ArticlePediatric nephrology (Berlin, Germany)2023

Hyperkalemia in pediatric chronic kidney disease.

Katherine L Kurzinski, Yunwen Xu, Derek K Ng, Susan L Furth, George J Schwartz, Bradley A Warady, CKiD Study Investigators

Registry-linked trialOpen access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pediatric nephrology (Berlin, Germany), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00327860 (Chronic Kidney Disease in Children Prospective Cohort Study), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00327860 recruitingnot on this map

Chronic Kidney Disease in Children Prospective Cohort Study (CKiD)

TypeobservationalSponsorJohns Hopkins Bloomberg School of Public HealthRan2003 to 2028Enrolled1,300ConditionsChronic Kidney Disease
3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Katherine L KurzinskiDivision of Pediatric Nephrology, Children's Mercy Kansas City, Kansas City, MO, USA.
Yunwen XuDepartment of Epidemiology, John's Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Derek K NgDepartment of Epidemiology, John's Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Susan L FurthDivision of Nephrology, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
George J SchwartzDivision of Pediatric Nephrology, University of Rochester Medical Center, Rochester, NY, USA.
Bradley A WaradyDivision of Pediatric Nephrology, Children's Mercy Kansas City, Kansas City, MO, USA. bwarady@cmh.edu.ORCID http://orcid.org/0000-0003-1812-6587
CKiD Study Investigators
Children's Mercy Hospital · USJohns Hopkins University · USChildren's Hospital of Philadelphia · USUniversity of Rochester Medical Center · US

Funding

Chronic Kidney Disease in Children Study (C-Kid)U01DK066174 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI SUSAN L. FURTH · 2003 to 2026
$25.1M
CKiD Cardiovascular Testing Travel SupplementU01DK066143 · NIDDK · CHILDREN'S MERCY HOSP (KANSAS CITY, MO) · PI Bradley Alan Warady · 2003 to 2026
$24.2M
The Kidney Disease in Children Data Management and Analysis Center (KIDMAC)U24DK066116 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI Derek K Ng · 2018 to 2026
$12.6M
Central Biochemistry Laboratory of the CKID ConsortiumU24DK082194 · NIDDK · UNIVERSITY OF ROCHESTER · PI SCHWARTZ, GEORGE J · 2018 to 2022
$1.7M
NIDDK NIH HHS U01 DK066143NIDDK NIH HHS U01 DK066174NIDDK NIH HHS U24 DK066116NIDDK NIH HHS U24 DK082194
6 · The paper itself

Abstract

backgroundWhile hyperkalemia is well described in adult chronic kidney disease (CKD), large studies evaluating potassium trends and risk factors for hyperkalemia in pediatric CKD are lacking. This study aimed to characterize hyperkalemia prevalence and risk factors in pediatric CKD.

methodsCross-sectional analysis of Chronic Kidney Disease in Children (CKiD) study data evaluated median potassium levels and percentage of visits with hyperkalemia (K ≥5.5 mmoL/L) in relation to demographics, CKD stage, etiology, proteinuria, and acid-base status. Multiple logistic regression was used to identify risk factors for hyperkalemia.

resultsOne thousand and fifty CKiD participants with 5183 visits were included (mean age 13.1 years, 62.7% male, 32.9% self-identifying as African American or Hispanic). A percentage of 76.6% had non-glomerular disease, 18.7% had CKD stage 4/5, 25.8% had low CO

conclusionsHyperkalemia was observed more frequently in children with advanced stage CKD, glomerular disease, low CO

Indexed as

HyperkalemiaKidney Failure, ChronicRenal Insufficiency, ChronicAdolescentAdultAngiotensin-Converting Enzyme InhibitorsAngiotensin Receptor AntagonistsCarbon DioxideChildCross-Sectional StudiesFemaleHumansMalePotassiumAngiotensin-Converting Enzyme InhibitorsAngiotensin Receptor AntagonistsCarbon DioxidePotassiumHyperkalemiaPediatric chronic kidney disease

Identifiers

PMID36939915
PMCPMC10550342
OpenAlexW4327895846

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.