ArticlePediatric surgery international2023
Nomogram for predicting fulminant necrotizing enterocolitis.
Article in Pediatric surgery international, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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13 citing papers in PubMed, 14 citations in OpenAlex.
- Validation of a Predictive Nomogram for Mortality Among Neonates With Necrotizing Enterocolitis in Tertiary Care Hospitals at Bahir Dar City, Bahir Dar, Northwest Ethiopia.Clinical medicine insights. Pediatrics · 2026Article
- Construction and validation of a predictive model for mortality risk in patients with Staphylococcus aureus bloodstream infection.BMC infectious diseases · 2026Article
- Surgical Necrotising Enterocolitis (S-NEC): Where We Stand Today: A Narrative Review.Journal of clinical medicine · 2026Review
- Clinical characteristics of necrotizing enterocolitis occurring within the first week of life in low-birth-weight preterm infants: a multicenter retrospective study.Frontiers in medicine · 2026Article
- Elevated day-2 hemoglobin P₅₀ and risk of necrotizing enterocolitis in preterm infants: a pilot study.Pediatric surgery international · 2025Article
- The prediction models for the optimal timing of surgical intervention for necrotizing enterocolitis: nomogram vs. five machine learning models.Pediatric surgery international · 2025Article
- Fulminant necrotizing enterocolitis: clinical features and a predictive model.BMC pediatrics · 2025Article
- A Nomogram for Predicting Surgical Risk in Neonates with Necrotizing Enterocolitis: A Retrospective Cohort Study.Indian journal of pediatrics · 2025Article
- Diagnostic and Prognostic Value of Hematological Parameters in Necrotizing Enterocolitis: A Systematic Review.Journal of clinical medicine · 2025Review
- Value of portal venous gas and a nomogram for predicting severe neonatal necrotizing enterocolitis.Pediatric research · 2025Article
- Observational
- Neurodevelopmental impairment following surgical necrotizing enterocolitis with gestational age ≥ 28 weeks: who is at risk?Pediatric surgery international · 2024Article
- Construction and evaluation of a risk model for adverse outcomes of necrotizing enterocolitis based on LASSO-Cox regression.Frontiers in pediatrics · 2024Article
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundFulminant necrotizing enterocolitis (FNEC) is the most serious subtype of NEC and has a high mortality rate and a high incidence of sequelae. Onset prediction can help in the establishment of a customized treatment strategy. This study aimed to develop and evaluate a predictive nomogram for FNEC.
methodsWe conducted a retrospective observation to study the clinical data of neonates diagnosed with NEC (Bell stage ≥ IIB). Neonates were divided into the FNEC and NEC groups. A multivariate logistic regression model was used to construct the nomogram model. The performance of the nomogram was assessed using area under the curve, calibration analysis, and decision curve analysis.
resultsA total of 206 neonate cases were included, among which 40 (19.4%) fulfilled the definition of FNEC. The identified predictors were assisted ventilation after NEC onset; shock at NEC onset; feeding volumes before NEC onset; neutrophil counts on the day of NEC onset; and neutrophil, lymphocyte, and monocyte counts on day 1 after NEC onset. The nomogram exhibited good discrimination, with an area under the receiver operating characteristic curve of 0.884 (95% CI 0.825-0.943). The predictive model was well calibrated. Decision curve analysis confirmed the clinical usefulness of this nomogram.
conclusionA nomogram with a potentially effective application was developed to facilitate the individualized prediction of FNEC, with the hope of providing further direction for the early diagnosis of FNEC and timing of intervention.
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