Evidence map›Paper›PMID 36939861›Full record

ArticleArchives of gynecology and obstetrics2024

Associations between endometriosis and adverse pregnancy and perinatal outcomes: a population-based cohort study.

Amanuel T Gebremedhin, Vera R Mitter, Bereket Duko, Gizachew A Tessema, Gavin F Pereira

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Archives of gynecology and obstetrics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 2 pooled it
3.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 2 syntheses or guidelines pooled it, 14 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Endometriosis: a journey from infertility to fertility.Abdominal radiology (New York) · 2025
    Review
  5. Article
  6. Article
  7. Impact of Prior Cesarean Delivery on Pregnancy Outcomes and Hemorrhage Risks in Complete Placenta Previa: A Decade-Long Retrospective Analysis.Medical science monitor : international medical journal of experimental and clinical research · 2024
    Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 3 countries.

Amanuel T GebremedhinCurtin School of Population Health, Faculty of Health Sciences, Curtin University, Kent Street, GPO Box U1987, Bentley, WA, 6102, Australia. a.gebremedhin@curtin.edu.au.ORCID 0000-0003-2459-1805
Vera R MitterPharmacoEpidemiology and Drug Safety Research Group, Department of Pharmacy, and PharmaTox Strategic Research Initiative, Faculty of Mathematics and Natural Sciences, University of Oslo, Oslo, Norway.
Bereket DukoCurtin School of Population Health, Faculty of Health Sciences, Curtin University, Kent Street, GPO Box U1987, Bentley, WA, 6102, Australia.
Gizachew A TessemaCurtin School of Population Health, Faculty of Health Sciences, Curtin University, Kent Street, GPO Box U1987, Bentley, WA, 6102, Australia.
Gavin F PereiraCurtin School of Population Health, Faculty of Health Sciences, Curtin University, Kent Street, GPO Box U1987, Bentley, WA, 6102, Australia.
Curtin University · AUNorwegian Institute of Public Health · NOUniversity of Oslo · NO

Funding

National Health and Medical Research Council 1099655National Health and Medical Research Council 1173991National Health and Medical Research Council 1195716Norges Forskningsråd 262700
6 · The paper itself

Abstract

purposeTo examine the association between endometriosis and adverse pregnancy and perinatal outcomes (preeclampsia, placenta previa, and preterm birth).

methodsA population-based retrospective cohort study was conducted among 468,778 eligible women who contributed 912,747 singleton livebirths between 1980 and 2015 in Western Australia (WA). We used probabilistically linked perinatal and hospital separation data from the WA data linkage system's Midwives Notification System and Hospital Morbidity Data Collection databases. We used a doubly robust estimator by combining the inverse probability weighting with the outcome regression model to estimate adjusted risk ratios (RR) and 95% confidence intervals (CIs).

resultsThere were 19,476 singleton livebirths among 8874 women diagnosed with endometriosis. Using a doubly robust estimator, we found pregnancies in women with endometriosis to be associated with an increased risk of preeclampsia with RR of 1.18, 95% CI 1.11-1.26, placenta previa (RR 1.59, 95% CI 1.42-1.79) and preterm birth (RR 1.45, 95% CI 1.37-1.54). The observed association persisted after stratified by the use of Medically Assisted Reproduction, with a slightly elevated risk among pregnancies conceived spontaneously.

conclusionsIn this large population-based cohort, endometriosis is associated with an increased risk of preeclampsia, placenta previa, and preterm birth, independent of the use of Medically Assisted Reproduction. This may help to enhance future obstetric care among this population.

Indexed as

EndometriosisPlacenta PreviaPre-EclampsiaPremature BirthCohort StudiesFemaleHumansInfant, NewbornPregnancyPregnancy OutcomeRetrospective StudiesEndometriosisMedically assisted reproductionPlacenta previaPreeclampsiaPreterm birth

Identifiers

PMID36939861
PMCPMC10894157
OpenAlexW4327892935

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.