Evidence map›Paper›PMID 36939610›Full record

ArticleThe Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology2023

The Prevalence of Minimal Hepatic Encephalopathy in an Outpatient Hepatology Clinic.

Deniz Eyice, Ayşe Merve Ok, Abdullah Sonsuz, Mustafa Şükrü Şenocak, Meliha Nur Durak, Sebati Özdemir, Billur Canbakan, Murat Tuncer, Ibrahim Hatemi

Open access · diamondAbstract read
In one paragraph

Article in The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. RE: Is There a More Practical Way for Screening Minimal Hepatic Encephalopathy?The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2023
    Article
  2. Is There a More Practical Way for Screening Minimal Hepatic Encephalopathy?The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Deniz EyiceDepartment of Internal Medicine, Cerrahpaşa School of Medicine, İstanbul University-Cerrahpaşa, İstanbul, Turkey.
Ayşe Merve OkDepartment of Internal Medicine, Cerrahpaşa School of Medicine, İstanbul University-Cerrahpaşa, İstanbul, Turkey.
Abdullah SonsuzDivision of Gastroenterology, Department of Internal Medicine, Cerrahpaşa School of Medicine, İstanbul University-Cerrahpaşa, İstanbul, Turkey.
Mustafa Şükrü ŞenocakDivision of Gastroenterology, Department of Internal Medicine, Cerrahpaşa School of Medicine, İstanbul University-Cerrahpaşa, İstanbul, Turkey.
Meliha Nur DurakDepartment of Biostatistics, Cerrahpaşa School of Medicine, İstanbul University-Cerrahpaşa, İstanbul, Turkey.
Sebati ÖzdemirDivision of Gastroenterology, Department of Internal Medicine, Cerrahpaşa School of Medicine, İstanbul University-Cerrahpaşa, İstanbul, Turkey.
Billur CanbakanDivision of Gastroenterology, Department of Internal Medicine, Cerrahpaşa School of Medicine, İstanbul University-Cerrahpaşa, İstanbul, Turkey.
Murat TuncerDivision of Gastroenterology, Department of Internal Medicine, Cerrahpaşa School of Medicine, İstanbul University-Cerrahpaşa, İstanbul, Turkey.
Ibrahim HatemiDivision of Gastroenterology, Department of Internal Medicine, Cerrahpaşa School of Medicine, İstanbul University-Cerrahpaşa, İstanbul, Turkey.
Istanbul University-Cerrahpaşa · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMinimal hepatic encephalopathy can only be detected by specific psychometric or neuropsychological tests. We aimed to determine the prevalence of minimal hepatic encephalopathy in a hepatology outpatient clinic of a tertiary center.

methodsA total of 82 patients with chronic liver disease were involved prospectively in this study. Control groups consisted of healthy volunteers (n = 123) and chronic renal failure patients (n = 28). We used 2 different methods to detect minimal hepatic encephalopathy. First method was a battery of 5 psychometric tests (number connection tests A and B, digit symbol test, serial dot test, line tracing test) which was filled by all patients. The second method was critical flicker frequency test. Both methods were used in the whole group (n = 233). We applied linear regression analysis to the results of psychometric tests of healthy volunteers to establish equations to calculate the expected values of each test. Test results of the patients were evaluated according to the expected results obtained from these equations.

resultsThe prevalence of minimal hepatic encephalopathy detected by psychometric tests and critical flicker frequency test was 13% and 14%, respectively. When the positivity of both tests was deemed necessary to diagnose minimal hepatic encephalopathy, the rate of minimal hepatic encephalopathy was 3.6% (n = 3) in a chronic liver disease patient group.

conclusionMinimal hepatic encephalopathy is a difficult clinical condition to diagnose, and it is more appropriate to use psychometric tests and critical flicker frequency test together.

Indexed as

GastroenterologyHepatic EncephalopathyLiver DiseasesHumansLiver CirrhosisOutpatientsPrevalencePsychometrics

Identifiers

PMID36939610
PMCPMC10334691
OpenAlexW4327741765

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.