Evidence map›Paper›PMID 36939339›Full record

ArticlemBio2023

Listeria monocytogenes GlmR Is an Accessory Uridyltransferase Essential for Cytosolic Survival and Virulence.

Daniel A Pensinger, Kimberly V Gutierrez, Hans B Smith, William J B Vincent, David S Stevenson, Katherine A Black, Krizia M Perez-Medina, Joseph P Dillard, Kyu Y Rhee, Daniel Amador-Noguez and 2 more

Open access · goldAbstract read
In one paragraph

Article in mBio, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
3.7field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Staying in the loop to make ends meet: roles and regulation of GlmR inbioRxiv : the preprint server for biology · 2025
    Article
  5. Article
  6. The role ofJournal of bacteriology · 2024
    Article
  7. Article
  8. Article
  9. Infection and immunity · 2023
    Article
  10. Review
  11. bioRxiv : the preprint server for biology · 2023
    Article
  12. Article
  13. eLife · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Daniel A Pensinger *Department of Medical Microbiology and Immunology, University of Wisconsin-Madison, Madison, Wisconsin, USA.ORCID 0000-0002-6742-5527
Kimberly V Gutierrez *Department of Medical Microbiology and Immunology, University of Wisconsin-Madison, Madison, Wisconsin, USA.ORCID 0009-0002-8604-9384
Hans B SmithDepartment of Medical Microbiology and Immunology, University of Wisconsin-Madison, Madison, Wisconsin, USA.ORCID 0000-0002-6456-4142
William J B VincentDepartment of Medical Microbiology and Immunology, University of Wisconsin-Madison, Madison, Wisconsin, USA.
David S StevensonDepartment of Bacteriology, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Katherine A BlackWeill Cornell Medical College, New York, New York, USA.
Krizia M Perez-MedinaDepartment of Medical Microbiology and Immunology, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Joseph P DillardDepartment of Medical Microbiology and Immunology, University of Wisconsin-Madison, Madison, Wisconsin, USA.ORCID 0000-0003-1711-7670
Kyu Y RheeWeill Cornell Medical College, New York, New York, USA.
Daniel Amador-NoguezMicrobiology Doctoral Training Program, University of Wisconsin-Madison, Madison, Wisconsin, USA.ORCID 0000-0002-3568-3070
TuAnh N HuynhMicrobiology Doctoral Training Program, University of Wisconsin-Madison, Madison, Wisconsin, USA.ORCID 0000-0002-7313-6166
John-Demian SauerDepartment of Medical Microbiology and Immunology, University of Wisconsin-Madison, Madison, Wisconsin, USA.ORCID 0000-0001-9367-794X
University of Wisconsin–Madison · USCornell University · US

Funding

GRADUATE TRAINING IN MOLECULAR BIOSCIENCEST32GM007215 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI HULL, CHRISTINA M · 1985 to 2018
$22.5M
Peptidoglycan metabolism and fragment releaseR01AI097157 · NIAID · UNIVERSITY OF WISCONSIN-MADISON · PI DILLARD, JOSEPH P · 2012 to 2022
$5.6M
Identification and Characterization of Genes Required for Listeria monocytogenes Cytosolic SurvivalR01AI137070 · NIAID · UNIVERSITY OF WISCONSIN-MADISON · PI SAUER, JOHN-DEMIAN · 2018 to 2022
$2.9M
The regulation of c-di-AMP homeostasis and signaling in bacteriaR35GM147519 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI Tu Anh Huynh · 2022 to 2026
$1.7M
NIAID NIH HHS R01 AI097157NIAID NIH HHS R01AI097157NIAID NIH HHS R01 AI137070NIAID NIH HHS R01AI137070NIGMS NIH HHS R35 GM147519NIGMS NIH HHS T32 GM007215NIGMS NIH HHS T32GM007215
6 · The paper itself

Abstract

The cytosol of eukaryotic host cells is an intrinsically hostile environment for bacteria. Understanding how cytosolic pathogens adapt to and survive in the cytosol is critical to developing novel therapeutic interventions against these pathogens. The cytosolic pathogen Listeria monocytogenes requires

Indexed as

Listeria monocytogenesBacterial ProteinsCell WallCytosolUDPglucose-Hexose-1-Phosphate UridylyltransferaseUridine DiphosphateVirulenceBacterial ProteinsUDPglucose-Hexose-1-Phosphate UridylyltransferaseUridine Diphosphatecell autonomous defensecytosolic pathogenGlmRListeria monocytogenespeptidoglycanuridyltransferase

Identifiers

PMID36939339
PMCPMC10128056
OpenAlexW4327893400

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.