Evidence map›Paper›PMID 36939335›Full record

ArticleInfection and immunity2023

Chemotaxis Coupling Protein CheW

Ching Wooen Sze, Chunhao Li

Open access · greenAbstract read
In one paragraph

Article in Infection and immunity, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.7field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Bacterial warfare at the molecular level:Current research in microbial sciences · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Ching Wooen SzeDepartment of Oral Craniofacial Molecular Biology, Virginia Commonwealth University, Richmond, Virginia, USA.
Chunhao LiDepartment of Oral Craniofacial Molecular Biology, Virginia Commonwealth University, Richmond, Virginia, USA.ORCID 0000-0002-1872-4870
Virginia Commonwealth University · US

Funding

Understanding Unique Aspects of Motility and Chemotaxis in Borrelia burgdorferiR01AI078958 · NIAID · VIRGINIA COMMONWEALTH UNIVERSITY · PI Chunhao Chris Li · 2008 to 2026
$5.7M
Toward novel therapies against Lyme disease through the inhibition of lysinoalaine cross-linking in the bacterial flagella.R01AI148844 · NIAID · CORNELL UNIVERSITY · PI CRANE, BRIAN R, LI, CHUNHAO CHRIS · 2021 to 2024
$2.4M
NIAID NIH HHS AI078958NIAID NIH HHS R01 AI078958NIAID NIH HHS R01 AI148844
6 · The paper itself

Abstract

The bacterial chemotaxis regulatory circuit mainly consists of coupling protein CheW, sensor histidine kinase CheA, and response regulator CheY. Most bacteria, such as Escherichia coli, have a single gene encoding each of these proteins. Interestingly, the Lyme disease pathogen, Borreliella burgdorferi, has multiple chemotaxis proteins, e.g., two CheA, three CheW, and three CheY proteins. The genes encoding these proteins mainly reside in two operons:

Indexed as

Bacterial ProteinsBorrelia burgdorferiChemotaxisPeriplasmic ProteinsAnimalsEscherichia coliMethyl-Accepting Chemotaxis ProteinsMiceMice, SCIDVirulenceBacterial ProteinsCheW2 protein, Borreliella burgdorferiMethyl-Accepting Chemotaxis ProteinsPeriplasmic ProteinsBorrelia burgdorferiBosRchemotaxisgene regulationLyme disease

Identifiers

PMID36939335
PMCPMC10112267
OpenAlexW4327892728

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.