ArticleMolecular plant pathology2023
Integrative transcriptome and proteome analysis reveals maize responses to Fusarium verticillioides infection inside the stalks.
Article in Molecular plant pathology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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20 citing papers in PubMed, 25 citations in OpenAlex.
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- Advances in genetic and molecular mechanisms of crop resistance to stalk rot.Stress biology · 2026Review
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- Decoding Plant Immunity: Proteomics as a Biotechnological Tool for Crop Improvement.Advances in experimental medicine and biology · 2026Review
- Integrated Proteomic and Metabolomic Profiling of the Secretome ofJournal of fungi (Basel, Switzerland) · 2025Article
- Gene Mapping and Genetic Analysis of Maize Resistance to Stalk Rot.International journal of molecular sciences · 2025Article
- From Morphology to Multi-Omics: A New Age of Fusarium Research.Pathogens (Basel, Switzerland) · 2025Review
- Wheat Yellow Mosaic Virus P1 Inhibits ROS Accumulation to Facilitate Viral Infection.International journal of molecular sciences · 2025Article
- A Zinc Polyphenolic Compound Increases Maize Resistance Against Infection byPlants (Basel, Switzerland) · 2024Article
- The Critical Role of Phenylpropanoid Biosynthesis Pathway in Lily Resistance Against Gray Mold.International journal of molecular sciences · 2024Article
- Integrated multi-omics investigation revealed the importance of phenylpropanoid metabolism in the defense response ofHorticulture research · 2024Article
- Transcriptomic and Metabolomic Analyses Reveal the Role of Phenylalanine Metabolism in the Maize Response to Stalk Rot Caused byInternational journal of molecular sciences · 2024Article
- Transcriptomic-Proteomic Analysis Revealed the Regulatory Mechanism of Peanut in Response toInternational journal of molecular sciences · 2024Article
- Molecular insights and omics-based understanding of plant-microbe interactions under drought stress.World journal of microbiology & biotechnology · 2023Review
- Integrative transcriptome and proteome analysis reveals maize responses to Fusarium verticillioides infection inside the stalks.Molecular plant pathology · 2023Article
- Special issue: Genetics of maize-microbe interactions.Molecular plant pathology · 2023Article
- Article
- Genome-wide association study of maize resistance toFrontiers in plant science · 2023Article
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Authors and funding
10 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Fusarium stalk rot caused by Fusarium verticillioides is one of the most devastating diseases of maize that causes significant yield losses and poses potential security concerns for foods worldwide. The underlying mechanisms of maize plants regulating defence against the disease remain poorly understood. Here, integrative proteomic and transcriptomic analyses were employed to identify pathogenesis-related protein genes by comparing differentially expressed proteins (DEPs) and differentially expressed genes (DEGs) in maize stalks after inoculation with F. verticillioides. Functional enrichment analysis showed that DEGs and DEPs were mainly enriched in glutathione metabolism, starch and sucrose metabolism, amino sugar and nucleotide sugar metabolism, linoleic acid metabolism, and phenylpropanoid biosynthesis. Fourteen DEGs and DEGs that were highly elevated after inoculation with F. verticillioides were confirmed with parallel reaction monitoring and reverse transcription-quantitative PCR, demonstrating the accountability and reliability of proteomic and transcriptomic data. We also assessed the potential roles of defence-related genes ZmCTA1, ZmWIP1, and ZmLOX2, identified from the multi-omics analysis, during the process of F. verticillioides infection through virus-induced gene silencing. The elevation of stalk rot symptomatic characteristics in the silenced plants revealed their contribution to resistance. We further functionally characterized the roles of ZmLOX2 expression in the defence response of maize plants conditioning fungal invasion via the salicylic acid-dependent pathway. Collectively, this study provides a comprehensive analysis of transcriptome and proteome of maize stalks following F. verticillioides inoculation, and defence-related genes that could inform selection of new genes as targets in breeding strategies.
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