Evidence map›Paper›PMID 36938806›Full record

ArticleEpidemiology and infection2023

Comparative transmission of SARS-CoV-2 Omicron (B.1.1.529) and Delta (B.1.617.2) variants and the impact of vaccination: national cohort study, England.

Hester Allen, Elise Tessier, Charlie Turner, Charlotte Anderson, Paula Blomquist, David Simons, Alessandra Løchen, Christopher I Jarvis, Natalie Groves, Fernando Capelastegui and 13 more

Abstract read
In one paragraph

Article in Epidemiology and infection, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
57citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

57 citing papers in PubMed, 5 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors.

Hester AllenCOVID-19 Vaccines and Epidemiology Division, UK Health Security Agency, Colindale, 61 Colindale Avenue, London NW9 5EQ, UK.ORCID 0000-0001-7213-5471
Elise TessierCOVID-19 Vaccines and Epidemiology Division, UK Health Security Agency, Colindale, 61 Colindale Avenue, London NW9 5EQ, UK.
Charlie TurnerField Service, UK Health Security Agency, London NW9 5EQ, UK.
Charlotte AndersonField Service, UK Health Security Agency, London NW9 5EQ, UK.
Paula BlomquistField Service, UK Health Security Agency, London NW9 5EQ, UK.
David SimonsField Service, UK Health Security Agency, London NW9 5EQ, UK.
Alessandra LøchenField Service, UK Health Security Agency, London NW9 5EQ, UK.
Christopher I JarvisField Service, UK Health Security Agency, London NW9 5EQ, UK.
Natalie GrovesGenomics Cell, UK Health Security Agency, London NW9 5EQ, UK.
Fernando CapelasteguiCOVID-19 Vaccines and Epidemiology Division, UK Health Security Agency, Colindale, 61 Colindale Avenue, London NW9 5EQ, UK.
Joe FlannaganCOVID-19 Vaccines and Epidemiology Division, UK Health Security Agency, Colindale, 61 Colindale Avenue, London NW9 5EQ, UK.
Asad ZaidiCOVID-19 Vaccines and Epidemiology Division, UK Health Security Agency, Colindale, 61 Colindale Avenue, London NW9 5EQ, UK.ORCID 0000-0002-6420-2539
Cong ChenField Service, UK Health Security Agency, London NW9 5EQ, UK.
Christopher RawlinsonField Service, UK Health Security Agency, London NW9 5EQ, UK.
Gareth J HughesField Service, UK Health Security Agency, London NW9 5EQ, UK.
Dimple ChudasamaCOVID-19 Vaccines and Epidemiology Division, UK Health Security Agency, Colindale, 61 Colindale Avenue, London NW9 5EQ, UK.
Sophie NashCOVID-19 Vaccines and Epidemiology Division, UK Health Security Agency, Colindale, 61 Colindale Avenue, London NW9 5EQ, UK.ORCID 0000-0002-7717-6982
Simon ThelwallCOVID-19 Vaccines and Epidemiology Division, UK Health Security Agency, Colindale, 61 Colindale Avenue, London NW9 5EQ, UK.
Jamie Lopez-BernalImmunisation and Countermeasures Division, UK Health Security Agency, 61 Colindale Avenue, London NW9 5EQ, UK.
Gavin DabreraCOVID-19 Vaccines and Epidemiology Division, UK Health Security Agency, Colindale, 61 Colindale Avenue, London NW9 5EQ, UK.
André CharlettStatistics, Modelling and Economics Division, UK Health Security Agency, 61 Colindale Avenue, London NW9 5EQ, UK.
Meaghan KallCOVID-19 Vaccines and Epidemiology Division, UK Health Security Agency, Colindale, 61 Colindale Avenue, London NW9 5EQ, UK.
Theresa LamagniCOVID-19 Vaccines and Epidemiology Division, UK Health Security Agency, Colindale, 61 Colindale Avenue, London NW9 5EQ, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant (B.1.1.529) rapidly replaced Delta (B.1.617.2) to become dominant in England. Our study assessed differences in transmission between Omicron and Delta using two independent data sources and methods. Omicron and Delta cases were identified through genomic sequencing, genotyping and S-gene target failure in England from 5-11 December 2021. Secondary attack rates for named contacts were calculated in household and non-household settings using contact tracing data, while household clustering was identified using national surveillance data. Logistic regression models were applied to control for factors associated with transmission for both methods. For contact tracing data, higher secondary attack rates for Omicron

Indexed as

COVID-19SARS-CoV-2Cohort StudiesEnglandHumansVaccinationContact tracingEnglandepidemicsOmicronpopulation surveillanceSARS-CoV-2transmissibilityvaccination

Identifiers

PMID36938806
PMCPMC10125873

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.