Evidence map›Paper›PMID 36938423›Full record

ArticleHeliyon2023

Imaging features of primary hepatic sarcomatoid carcinoma: Differentiation from hepatocellular carcinoma and intrahepatic cholangiocarcinoma on CT: A preliminary study.

Lintao Chen, Shijian Ruan, Pan Wang, Yongna Cheng, Yubizhuo Wang, Wuwei Tian, Hongbin Zhang, Xiuming Zhang, Wenjie Liang

Open access · goldAbstract read
In one paragraph

Article in Heliyon, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Lintao ChenDepartment of Radiology, Yiwu Central Hospital, Yiwu, Zhejiang, China.
Shijian RuanCollege of Information Science & Electronic Engineering, Zhejiang University, Hangzhou, Zhejiang, China.
Pan WangDepartment of Radiology, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang, China.
Yongna ChengDepartment of Radiology, Yiwu Central Hospital, Yiwu, Zhejiang, China.
Yubizhuo WangDepartment of Radiology, Yiwu Central Hospital, Yiwu, Zhejiang, China.
Wuwei TianCollege of Information Science & Electronic Engineering, Zhejiang University, Hangzhou, Zhejiang, China.
Hongbin ZhangDepartment of Radiology, Yiwu Central Hospital, Yiwu, Zhejiang, China.
Xiuming ZhangDepartment of Pathology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.
Wenjie LiangDepartment of Radiology, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang, China.
Zhejiang University · CNFirst Affiliated Hospital Zhejiang University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: Primary hepatic sarcomatoid carcinoma (PHSC) is a rare type of malignant tumor in the liver. Nevertheless, few studies have focused on the imaging diagnosis of PHSC. In this study, we collected clinical and computed tomography (CT) imaging data of PHSC from two institutions, aiming to investigate the clinical and radiological characteristics of PHSC. Methods: We retrospectively investigated the clinical characteristics and CT features of 22 PHSC patients (19 males and 3 females; mean age, 63.4 years; range, 49 to 76 years), 95 hepatocellular carcinoma (HCC) patients and 50 intrahepatic cholangiocarcinoma (ICC) patients. Two radiologists independently evaluated the CT features of the three groups. Subsequently, we analyzed the differences in the clinical characteristics and CT features between the PHSC and control groups. Results: Most PHSCs were larger than 5 cm (72.7%). PHSC mainly showed irregular (81.8%), heterogeneous (100%) masses with ill-defined (72.7%) borders with necrosis (86.4%) on CT, which are more common CT features versus HCC ( Conclusions: PHSC generally presents as irregularly large masses with necrosis, intrahepatic metastasis, and lymphadenopathy. The CT enhancement of PHSC is mainly part of APHE and delayed progressive enhancement.

Indexed as

AFP, alpha-fetoproteinAPHE, arterial phase hyperenhancementCA125, carbohydrate antigen 12-5CA199, carbohydrate antigen 19-9CEA, carcinoembryonic antigenCKpan, pan-cytokeratinComputed tomographyCT, computed tomographyGPC3, glypican-3HCC, hepatocellular carcinomaH&E, hematoxylin-eosinHepatic sarcomatoid carcinomaHepatocellular carcinomaICC, intrahepatic cholangiocarcinomaImagingIntrahepatic cholangiocarcinomaMRI, magnetic resonance imagingPHSC, primary hepatic sarcomatoid carcinomaTACE, transcatheter arterial chemoembolization

Identifiers

PMID36938423
PMCPMC10018468
OpenAlexW4322761400

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.