Evidence map›Paper›PMID 36938205›Full record

ArticleCureus2023

Dysregulation of miR-155 Expression in Professional Mixed Martial Arts (MMA) Fighters.

Dominick Cabrera, Kayla Thompson, Julius D Thomas, Corey Peacock, Jose Antonio, Jaime L Tartar, Aurelien Tartar

Open access · diamondFull text read
In one paragraph

Article in Cureus, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Dominick CabreraPsychology, Nova Southeastern University Dr. Kiran C. Patel College of Osteopathic Medicine, Davie, USA.
Kayla ThompsonPsychology, Nova Southeastern University, Davie, USA.
Julius D ThomasPsychology, Nova Southeastern University, Davie, USA.
Corey PeacockCollege of Health Care Sciences, Nova Southeastern University, Davie, USA.
Jose AntonioCollege of Health Care Sciences, Nova Southeastern University, Davie, USA.
Jaime L TartarPsychology, Nova Southeastern University, Davie, USA.
Aurelien TartarBiological Sciences, Nova Southeastern University, Davie, USA.
Southeastern University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Psychological and physical stress can induce dysregulation of gene expression via changes in DNA methylation and microRNA (miRNA) expression. Such epigenetic modifications are yet to be investigated in professional Mixed Martial Arts (MMA) fighters subject to highly stressful training involving repetitive head impacts. This study examined differences in DNA methylation and miRNA expression in elite MMA fighters compared to active controls. Global methylation differences between groups were assessed via a LINE-1 assay. At the same time, PCR arrays were used to estimate differential expression in samples of 21 fighters and 15 controls for 192 different miRNAs associated with inflammatory diseases. An Independent-Samples

Indexed as

athletegene expression profilemirna signatureneuro inflammationtraumatic brain injury

Identifiers

PMID36938205
PMCPMC10017279
OpenAlexW4320481001

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read14
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.