ReviewKidney international reports2023
Why is Intradialytic Hypotension the Commonest Complication of Outpatient Dialysis Treatments?
Review in Kidney international reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
49 citing papers in PubMed, 3 syntheses or guidelines pooled it, 63 citations in OpenAlex.
- Ciprofol versus propofol and the risk of hemodynamic adverse events: a meta-analysis with trial sequential analysis of randomized controlled trials.BMC anesthesiology · 2026Pooled it
- Recommendations of the Brazilian Society of Nephrology for regulating access to outpatient dialysis in the Brazilian Unified Health System.Jornal brasileiro de nefrologia · 2026Guideline
- Guidelines for hospital nephrology assistance from the Brazilian Society of Nephrology (BSN).Jornal brasileiro de nefrologiaGuideline
- Effects of intradialytic nutrition on dialysis adequacy and fatigue in hemodialysis patients: a randomized crossover study.Revista da Escola de Enfermagem da U S P · 2026Trial
- Tenapanor Beyond Phosphate: Gut Sodium Transport, Stool Transit Time, and Volume Balance in Dialysis Patients.Hemodialysis international. International Symposium on Home Hemodialysis · 2026Review
- Renal diseases and blood pressure dysregulation in acute care: Pathophysiology, clinical patterns.World journal of nephrology · 2026Review
- Toward Precision Fluid Management in Hemodialysis: Adaptive Ultrafiltration Guided by Continuous Relative Blood Volume Monitoring.Journal of clinical medicine · 2026Article
- Gallstones and acute cholecystitis in CKD and dialysis: an underrecognized biliary burden in nephrology.Clinical and experimental nephrology · 2026Review
- Hemodiafiltration in Dialysis Practice: Global Adoption, Toxin Clearance, Inflammation Control, and Clinical Safety.Toxins · 2026Review
- Article
- A Narrative Summary of Strategies to Mitigate Intradialytic Hypotension in Poisoned Patients Requiring Extracorporeal Toxin Elimination.Journal of medical toxicology : official journal of the American College of Medical Toxicology · 2026Review
- Effect of Ambient Temperature on Intradialytic Hypotension in Hemodialysis Patients: A Retrospective Cohort Study.Kidney medicine · 2026Article
- Mechanical thromboprophylaxis for preventing intradialytic hypotension in people undergoing maintenance haemodialysis.The Cochrane database of systematic reviews · 2026Article
- Hemodialysis-related allergic reactions: a retrospective cohort study of clinical presentations, etiologies, and management.BMC nephrology · 2026Article
- Dialysis-associated cardiovascular disease risk in children: mechanism and management.Pediatric nephrology (Berlin, Germany) · 2026Review
- A dynamic bioreactor for endothelial and epithelial cell co-culture to mimic aspects of renal microenvironments.Biomedical microdevices · 2026Article
- Intradialytic Hypotensive Episodes are Only Occasionally Associated With Adverse Symptoms.Kidney international reports · 2026Article
- Updates in the management of intradialytic hypotension: Emerging strategies and innovations.World journal of nephrology · 2025Review
- Choosing the right antihypertensive drug to avoid intradialytic hypotension.Clinical kidney journal · 2025Article
- Predicting blood pressure variability in hemodialysis using an explainable boosting machine model.Clinical kidney journal · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Intradialytic hypotension (IDH) is the most frequent complication of hemodialysis (HD) treatments with a frequency of 10% to 12% for patients with chronic kidney disease attending for outpatient treatments and is associated with both temporary ischemic stress to vital organs, including the heart and brain, and increased patient mortality. Although there have been many different definitions of IDH over the years, an absolute nadir systolic blood pressure (SBP) has the strongest association with patient outcomes. The unifying pathophysiology is one of reduced effective blood volume, resulting in lower plasma tonicity, and if this cannot be adequately compensated for by activation of neurohumeral systems, then arteriolar tone and blood pressure fall. The risk factors for developing IDH are numerous, ranging from patient-related factors, including age and comorbidity with reduced cardiac reserve, to patient compliance with dietary and lifestyle advice, to reactions with the extracorporeal circuit and medications, choice of dialysate composition and temperature, setting of postdialysis target weight, ultrafiltration rate, and profiling. Advances in dialysis machine technology by providing real time estimates of the effective circulating volume and adjusting dialysate composition to maintain vascular tonicity are being developed, but currently require more sophisticated biofeedback loops to be clinically effective in preventing IDH. While awaiting advances in artificial intelligence, the clinician continues to rely on patient education to limit interdialytic weight gains, frequent assessment of the postdialysis target weight, adjusting dialysate composition and temperature, introducing convective therapies to increase thermal losses, and altering dialysis session duration and frequency to reduce ultrafiltration rate requirements.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.