Evidence map›Paper›PMID 36937923›Full record

ArticleFrontiers in cardiovascular medicine2023

Muscle progenitor cells are required for skeletal muscle regeneration and prevention of adipogenesis after limb ischemia.

Hasan Abbas, Lindsey A Olivere, Michael E Padgett, Cameron A Schmidt, Brian F Gilmore, Timothy J McCord, Kevin W Southerland, Joseph M McClung, Christopher D Kontos

Open access · goldFull text read
In one paragraph

Article in Frontiers in cardiovascular medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Hasan AbbasDepartment of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, NC, United States.
Lindsey A OlivereDuke University School of Medicine, Durham, NC, United States.
Michael E PadgettDepartment of Medicine, Division of Cardiology, Duke University Medical Center, Durham, NC, United States.
Cameron A SchmidtDepartment of Physiology, Brody School of Medicine, East Carolina University, Greenville, NC, United States.
Brian F GilmoreDepartment of Surgery, Duke University Medical Center, Durham, NC, United States.
Timothy J McCordDepartment of Cell Biology, Duke University School of Medicine, Durham, NC, United States.
Kevin W SoutherlandDepartment of Surgery, Duke University Medical Center, Durham, NC, United States.
Joseph M McClungDepartment of Physiology, Brody School of Medicine, East Carolina University, Greenville, NC, United States.
Christopher D KontosDepartment of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, NC, United States.
Duke Medical Center · USDuke University · USEast Carolina University · USDuke-NUS Medical School · SG

Funding

Cell and Molecular Biology Training ProgramT32GM142605 · NIGMS · DUKE UNIVERSITY · PI MICHAEL S BOYCE, Stefano Di Talia · 2021 to 2026
$3.7M
Variant Determinants of African American Limb Pathology in Peripheral Arterial DiseaseR01HL157659 · NHLBI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI MCCLUNG, JOSEPH MATTHEW · 2021 to 2024
$2.6M
Mechanisms Regulating Vascular HomeostasisR01HL156009 · NHLBI · DUKE UNIVERSITY · PI KONTOS, CHRISTOPHER D · 2021 to 2024
$2.2M
Skeletal Muscle and Vascular Remodeling in Peripheral Artery DiseaseR01HL124444 · NHLBI · DUKE UNIVERSITY · PI KONTOS, CHRISTOPHER D · 2015 to 2017
$1.4M
NHLBI NIH HHS R01 HL124444NHLBI NIH HHS R01 HL156009NHLBI NIH HHS R01 HL157659NIGMS NIH HHS T32 GM142605
6 · The paper itself

Abstract

Skeletal muscle injury in peripheral artery disease (PAD) has been attributed to vascular insufficiency, however evidence has demonstrated that muscle cell responses play a role in determining outcomes in limb ischemia. Here, we demonstrate that genetic ablation of Pax7

Indexed as

adipogenesiscritical limb threatening ischemiafibro/adipogenic progenitor cellshind limb ischemiamuscle progenitor cellsperipheral artery diseaseskeletal muscle regeneration

Identifiers

PMID36937923
PMCPMC10017542
OpenAlexW4322773589

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read73
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.