Evidence map›Paper›PMID 36937762›Full record

ArticleFrontiers in bioengineering and biotechnology2023

Bio-inspired aptamers decorated gold nanoparticles enable visualized detection of malathion.

Peng Li, Haonan Zhan, Sijian Tao, Zhuohao Xie, Jiahao Huang

Open access · goldFull text read
In one paragraph

Article in Frontiers in bioengineering and biotechnology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Peng LiSchool of Biomedical Engineering, Southern Medical University, Guangzhou , China.
Haonan ZhanSchool of Biomedical Engineering, Southern Medical University, Guangzhou , China.
Sijian TaoSchool of Biomedical Engineering, Southern Medical University, Guangzhou , China.
Zhuohao XieSchool of Biomedical Engineering, Southern Medical University, Guangzhou , China.
Jiahao HuangSchool of Biomedical Engineering, Southern Medical University, Guangzhou , China.
Southern Medical University · CNGuangdong Medical College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Biosensors always respond to the targets of interest in a specific manner, employing biological or bio-mimic recognition elements such as antibodies and aptamers. Inspired by target recognition in nature, an aptamer-mediated, gold nanoparticle-based sensing approach is developed in this work for effective determination of malathion. The sensing system consists of negatively charged aptamer probes, and polycationic proteins, protamine, as well as exceptional colorimetric nanoprobes, barely gold nanoparticles (AuNPs). Protamine molecules bound to aptamer probes hinder the aggregation of AuNPs, while no such inhibition is maintained when aptamer-specific malathion is introduced into the solution, thus leading to the solution colour change from red to blue observable by the naked eye. The assay is accomplished

Indexed as

bio-inspired recognition componentsbiosensorcolorimetric assayenzyme-free systemsuper-hydrophilic nanomaterial

Identifiers

PMID36937762
PMCPMC10020530
OpenAlexW4323044797

What OpenQuestion holds

Textfull text, public
LicenceCC BY
reference markers read13
measurements read38
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.