Evidence map›Paper›PMID 36937639›Full record

ArticleClinical case reports2023

Infection and myelodysplasia: A case report of GATA2 deficiency in a South African patient.

Erica-Mari Nell, Helena Cornellissen, Katherine Hodkinson, Michael F Urban, Fatima Cassim Bassa, Fatima Bibi Fazel, Tracey Wiggill, Semira Irusen, Zivanai C Chapanduka

Open access · goldFull text readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical case reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Erica-Mari NellDivision of Haematological Pathology, Faculty of Medicine and Health Sciences Stellenbosch University and National Health Laboratory Service, Tygerberg Hospital Cape Town South Africa.ORCID https://orcid.org/0000-0002-7932-3210
Helena CornellissenDivision of Haematological Pathology, Faculty of Medicine and Health Sciences Stellenbosch University and National Health Laboratory Service, Tygerberg Hospital Cape Town South Africa.
Katherine HodkinsonDepartment of Molecular Medicine and Haematology, Faculty of Health Sciences University of the Witwatersrand and National Health Laboratory Service Johannesburg South Africa.
Michael F UrbanDivision of Molecular Biology and Human Genetics, Faculty of Medicine and Health Science Stellenbosch University Stellenbosch South Africa.ORCID https://orcid.org/0000-0002-9392-0206
Fatima Cassim BassaDivision of Clinical Haematology, Department of Internal Medicine, Faculty of Medicine and Health Sciences Stellenbosch University and Tygerberg Hospital Cape Town South Africa.
Fatima Bibi FazelDivision of Clinical Haematology, Department of Internal Medicine, Faculty of Medicine and Health Sciences Stellenbosch University and Tygerberg Hospital Cape Town South Africa.
Tracey WiggillDepartment of Molecular Medicine and Haematology, Faculty of Health Sciences University of the Witwatersrand and National Health Laboratory Service Johannesburg South Africa.ORCID https://orcid.org/0000-0001-8761-2162
Semira IrusenDivision of Clinical Haematology, Department of Internal Medicine, Faculty of Medicine and Health Sciences Stellenbosch University and Tygerberg Hospital Cape Town South Africa.
Zivanai C ChapandukaDivision of Haematological Pathology, Faculty of Medicine and Health Sciences Stellenbosch University and National Health Laboratory Service, Tygerberg Hospital Cape Town South Africa.
National Health Laboratory Service · ZAStellenbosch University · ZA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rare diseases often result in delays in diagnosis. It is important to recognize conditions that have features of both inborn errors of immunity and predispose to myeloid neoplasia. Here we report a patient with GATA2 deficiency that presented with disseminated non-tuberculous mycobacterial infection and pancytopenia secondary to myelodysplastic syndrome.

Indexed as

GATA2 deficiencyinborn errors of immunitylymphoedemamyelodysplastic syndromemyeloid neoplasms with germline predispositionnon‐tuberculous mycobacterium

Identifiers

PMID36937639
PMCPMC10014512
OpenAlexW4324374152

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read18
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.