ArticleFrontiers in cellular neuroscience2023
Large-scale analyses of CAV1 and CAV2 suggest their expression is higher in post-mortem ALS brain tissue and affects survival.
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In one paragraph
Article in Frontiers in cellular neuroscience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 23% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.
- Mutations in the tail and rod domains of the neurofilament heavy-chain gene increase the risk of ALS.Annals of clinical and translational neurology · 2024Pooled it
- Entering the era of precision medicine to treat amyotrophic lateral sclerosis.Molecular neurodegeneration · 2025Review
- Early Alterations in Structural and Functional Properties in the Neuromuscular Junctions of Mutant FUS Mice.International journal of molecular sciences · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
33 authors at 20 institutions in 12 countries.
Brett N AdeySocial Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, United Kingdom.
Johnathan Cooper-KnockSheffield Institute for Translational Neuroscience (SITraN), University of Sheffield, Sheffield, United Kingdom.
Ahmad Al KhleifatDepartment of Basic and Clinical Neuroscience, Maurice Wohl Clinical Neuroscience Institute, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, United Kingdom.
Isabella FoghDepartment of Basic and Clinical Neuroscience, Maurice Wohl Clinical Neuroscience Institute, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, United Kingdom.
Philip van DammeDepartment of Neurosciences, KU Leuven-University of Leuven, Experimental Neurology and Leuven Brain Institute (LBI), Leuven, Belgium.
Philippe CorciaUMR 1253, Université de Tours, Inserm, Tours, France.
Philippe CouratierCentre de référence sur la SLA, CHRU de Limoges, Limoges, France.
Orla HardimanAcademic Unit of Neurology, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland.
Russell McLaughlinComplex Trait Genomics Laboratory, Smurfit Institute of Genetics, Trinity College Dublin, Dublin, Ireland.
Marc GotkineFaculty of Medicine, Hebrew University of Jerusalem, Jerusalem, Israel.
Vivian DroryDepartment of Neurology, Tel-Aviv Sourasky Medical Centre, Tel-Aviv, Israel.
Vincenzo SilaniDepartment of Neurology and Laboratory of Neuroscience, Istituto Auxologico Italiano, IRCCS, Milan, Italy.
Nicola TicozziDepartment of Neurology and Laboratory of Neuroscience, Istituto Auxologico Italiano, IRCCS, Milan, Italy.
Jan H VeldinkDepartment of Neurology, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht, Netherlands.
Leonard H van den BergDepartment of Neurology, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht, Netherlands.
Mamede de CarvalhoInstituto de Fisiologia, Instituto de Medicina Molecular João Lobo Antunes, Faculdade de Medicina, Universidade de Lisboa, Lisbon, Portugal.
Susana PintoInstituto de Fisiologia, Instituto de Medicina Molecular João Lobo Antunes, Faculdade de Medicina, Universidade de Lisboa, Lisbon, Portugal.
Jesus S Mora PardinaALS Unit, Hospital San Rafael, Madrid, Spain.
Mónica Povedano PanadesFunctional Unit of Amyotrophic Lateral Sclerosis (UFELA), Service of Neurology, Bellvitge University Hospital, L'Hospitalet de Llobregat, Barcelona, Spain.
Peter M AndersenDepartment of Clinical Science, Umeå University, Umeå, Sweden.
Markus WeberNeuromuscular Diseases Unit/ALS Clinic, St. Gallen, Switzerland.
Nazli A BaşakKoc University School of Medicine, Translational Medicine Research Center, NDAL, Istanbul, Turkey.
Christopher E ShawDepartment of Basic and Clinical Neuroscience, Maurice Wohl Clinical Neuroscience Institute, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, United Kingdom.
Pamela J ShawSheffield Institute for Translational Neuroscience (SITraN), University of Sheffield, Sheffield, United Kingdom.
Karen E MorrisonSchool of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast, United Kingdom.
John E LandersDepartment of Neurology, University of Massachusetts Medical School, Worcester, MA, United States.
Jonathan D GlassDepartment of Neurology, Emory University School of Medicine, Atlanta, GA, United States.
Patrick Vourc'hDepartment of Neurology, University Hospitals Leuven, Leuven, Belgium.
Richard J B DobsonDepartment of Biostatistics and Health Informatics, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, United Kingdom.
Gerome BreenSocial Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, United Kingdom.
Ammar Al-ChalabiDepartment of Basic and Clinical Neuroscience, Maurice Wohl Clinical Neuroscience Institute, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, United Kingdom.
Ashley R JonesDepartment of Basic and Clinical Neuroscience, Maurice Wohl Clinical Neuroscience Institute, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, United Kingdom.
Alfredo IacoangeliDepartment of Biostatistics and Health Informatics, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, United Kingdom.
King's College London · GBNational Institute for Health Research · GBTrinity College Dublin · IEUniversity Medical Center Utrecht · NLUniversity of Lisbon · PTUniversity of Sheffield · GBBellvitge University Hospital · ESCentre Hospitalier Universitaire de Tours · FREmory University · USFerrari (Italy) · ITHebrew University of Jerusalem · ILHospital Universitario San Rafael · ESIRCCS Istituto Auxologico Italiano · ITKoç University · TRKU Leuven · BEQueen's University Belfast · GBTel Aviv University · ILUmeå University · SEUniversité de Limoges · FRUniversity of Massachusetts Chan Medical School · US
Funding
Medical Research Council MR/L501529/1Medical Research Council MR/R024804/1Wellcome Trust
Abstract
PubMed holds no abstract for this paper.
Indexed as
ALS (Amyotrophic lateral sclerosis)CavCAV1 and CAV2caveolindifferential expression analysis (DEA)enhancer variantneurodegenerationsurvival analysis
Identifiers
What OpenQuestion holds
Textfull text, public
LicenceCC BY
measurements read16
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.