Evidence map›Paper›PMID 36937091›Full record

ArticleJournal of the American Statistical Association2019

Bayesian Graphical Regression.

Yang Ni, Francesco C Stingo, Veerabhadran Baladandayuthapani

Abstract read
In one paragraph

Article in Journal of the American Statistical Association, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Connectivity Regression.Biostatistics (Oxford, England) · 2025
    Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Multi-task Learning for Gaussian Graphical Regressions with High Dimensional Covariates.Journal of computational and graphical statistics : a joint publication of American Statistical Association, Institute of Mathematical Statistics, Interface Foundation of North America · 2024
    Article
  10. Article
  11. Bayesian Spatial Blind Source Separation via the Thresholded Gaussian Process.Journal of the American Statistical Association · 2024
    Article
  12. Covariate-Assisted Bayesian Graph Learning for Heterogeneous Data.Journal of the American Statistical Association · 2024
    Article
  13. Federated Learning for Sparse Bayesian Models with Applications to Electronic Health Records and Genomics.Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing · 2023
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Bayesian graphical models for modern biological applications.Statistical methods & applications · 2022
    Review
  19. Bayesian Sparse Mediation Analysis with Targeted Penalization of Natural Indirect Effects.Journal of the Royal Statistical Society. Series C, Applied statistics · 2021
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Yang NiDepartment of Statistics and Data Sciences, The University of Texas at Austin.
Francesco C StingoDepartment of Biostatistics, The University of Texas MD Anderson Cancer Center.
Veerabhadran BaladandayuthapaniDepartment of Biostatistics, The University of Texas MD Anderson Cancer Center.

Funding

Tumor Evolution and Metastasis ProgramP30CA016672 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Scott Kopetz · 1985 to 2026
$290.8M
P4 -TARGETING MULTIPLE MYELOMA BY COMBINING CDK INHIBITORS AND BCL-2 ANTAGONISTSP50CA142509 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI KWAK, LARRY W · 2010 to 2014
$11.1M
Graph-based Bayesian analysis of Genomics and Proteomics DataR01CA194391 · NCI · TEXAS A&M UNIVERSITY · PI BALADANDAYUTHAPANI, VEERABHADRAN, MALLICK, BANI K · 2016 to 2020
$2.0M
Integrative methods for high-dimensional genomics dataR01CA160736 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI BALADANDAYUTHAPANI, VEERABHADRAN · 2011 to 2014
$1.4M
NCI NIH HHS P30 CA016672NCI NIH HHS P50 CA142509NCI NIH HHS R01 CA160736NCI NIH HHS R01 CA194391
6 · The paper itself

Abstract

We consider the problem of modeling conditional independence structures in heterogeneous data in the presence of additional subject-level covariates - termed Graphical Regression. We propose a novel specification of a conditional (in)dependence function of covariates - which allows the structure of a directed graph to vary flexibly with the covariates; imposes sparsity in both edge and covariate selection; produces both subject-specific and predictive graphs; and is computationally tractable. We provide theoretical justifications of our modeling endeavor, in terms of graphical model selection consistency. We demonstrate the performance of our method through rigorous simulation studies. We illustrate our approach in a cancer genomics-based precision medicine paradigm, where-in we explore gene regulatory networks in multiple myeloma taking prognostic clinical factors into account to obtain both population-level and subject-level gene regulatory networks.

Indexed as

Directed acyclic graphNon-local priorPredictive networkSubject-specific graphVarying graph structure

Identifiers

PMID36937091
PMCPMC10021014

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.