Evidence map›Paper›PMID 36936706›Full record

ArticleExperimental and therapeutic medicine2023

Protective effect of L‑carnitine against oxidative stress injury in human ovarian granulosa cells.

Xuening Li, Xiaodong Wu, Tianyi Ma, Yuemin Zhang, Pingping Sun, Dandan Qi, Huagang Ma

Open access · diamondAbstract read
In one paragraph

Article in Experimental and therapeutic medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. A Novel Role of DELTEX2 in Maintaining Genomic Stability of Granulosa Cells During Ovarian Aging.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026
    Article
  3. Article
  4. Frontiers in pharmacology · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Xuening LiSchool of Clinical Medicine, Weifang Medical University, Weifang, Shandong 261000, P.R. China.
Xiaodong WuSchool of Clinical Medicine, Weifang Medical University, Weifang, Shandong 261000, P.R. China.
Tianyi MaFaculty of Engineering and IT, University of Technology Sydney, Sydney, New South Wales 2007, Australia.
Yuemin ZhangCenter of Reproductive Medicine, Weifang People's Hospital, Weifang, Shandong 261000, P.R. China.
Pingping SunCenter of Reproductive Medicine, Weifang People's Hospital, Weifang, Shandong 261000, P.R. China.
Dandan QiCenter of Reproductive Medicine, Weifang People's Hospital, Weifang, Shandong 261000, P.R. China.
Huagang MaCenter of Reproductive Medicine, Weifang People's Hospital, Weifang, Shandong 261000, P.R. China.
Weifang People's Hospital · CNWeifang Medical University · CNUniversity of Technology Sydney · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Granulosa cells (GCs) are important for supporting and nourishing oocytes during follicular development and maturation. Oxidative stress (OS) injury of GCs can lead to decreased responsiveness of follicles to follicular stimulating hormone (FSH), which will accelerate ovarian senescence and adversely affect oocyte and embryo quality. Since L-carnitine has been previously reported to exert strong antioxidant activity, the present study aimed to explore the possible effects of L-carnitine on OS injury and FSH receptor (FSHR) expression in ovarian GCs, results of which may be of significance for GCs protection. In the present study, OS was induced

Indexed as

follicular stimulating hormone receptorL-carnitinemitochondriaovarian granulosa cellsoxidative stress

Identifiers

PMID36936706
PMCPMC10015319
OpenAlexW4321616563

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.