Evidence map›Paper›PMID 36936692›Full record

ArticleFrontiers in cell and developmental biology2023

Sec22b-dependent antigen cross-presentation is a significant contributor of T cell priming during infection with the parasite

Lucía Biscari, Ma Carmen Maza, Cecilia Farré, Cintia Daniela Kaufman, Sebastian Amigorena, Manuel Fresno, Núria Gironès, Andrés Alloatti

Open access · goldFull text read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in cell and developmental biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 3 countries.

Lucía BiscariInstituto de Inmunología Clínica y Experimental de Rosario (IDICER), CONICET, Universidad Nacional de Rosario, Rosario, Argentina.
Ma Carmen MazaDepartamento de Biología Molecular, Universidad Autónoma de Madrid (UAM), Madrid, Spain.
Cecilia FarréInstituto de Inmunología Clínica y Experimental de Rosario (IDICER), CONICET, Universidad Nacional de Rosario, Rosario, Argentina.
Cintia Daniela KaufmanInstituto de Inmunología Clínica y Experimental de Rosario (IDICER), CONICET, Universidad Nacional de Rosario, Rosario, Argentina.
Sebastian AmigorenaInstitut Curie, INSERM U932, Immunity and Cancer, PSL University, Paris, France.
Manuel FresnoDepartamento de Biología Molecular, Universidad Autónoma de Madrid (UAM), Madrid, Spain.
Núria GironèsDepartamento de Biología Molecular, Universidad Autónoma de Madrid (UAM), Madrid, Spain.
Andrés AlloattiInstituto de Inmunología Clínica y Experimental de Rosario (IDICER), CONICET, Universidad Nacional de Rosario, Rosario, Argentina.
Instituto de Biología Molecular y Celular de Rosario · ARUniversidad Autónoma de Madrid · ESCentro de Biología Molecular Severo Ochoa · ESConsejo Nacional de Investigaciones Científicas y Técnicas · ARNational University of Rosario · ARUniversité Paris Sciences et Lettres · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antigen cross-presentation is a vital mechanism of dendritic cells and other antigen presenting cells to orchestrate the priming of cytotoxic responses towards killing of infected or cancer cells. In this process, exogenous antigens are internalized by dendritic cells, processed, loaded onto MHC class I molecules and presented to CD8

Indexed as

antigen cross-presentationCD8 + T cellscre-loxp transgenic micedendritic cellsSec22b SNARE proteinTrypanosoma cruzi

Identifiers

PMID36936692
PMCPMC10014565
OpenAlexW4322745166

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read15
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.