Evidence map›Paper›PMID 36936686›Full record

ReviewFrontiers in cell and developmental biology2023

Mesenchymal "stem" cells, or facilitators for the development of regenerative macrophages? Pericytes at the interface of wound healing.

Renan Fava Marson, Andrea Pereira Regner, Lindolfo da Silva Meirelles

Full text readReview
In one paragraph

Review in Frontiers in cell and developmental biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Renan Fava MarsonGraduate Program in Cellular and Molecular Biology Applied to Health-PPGBioSaúde, Lutheran University of Brazil, Canoas, Brazil.
Andrea Pereira RegnerGraduate Program in Cellular and Molecular Biology Applied to Health-PPGBioSaúde, Lutheran University of Brazil, Canoas, Brazil.
Lindolfo da Silva MeirellesGraduate Program in Cellular and Molecular Biology Applied to Health-PPGBioSaúde, Lutheran University of Brazil, Canoas, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cultured mesenchymal stromal cells are among the most used cells in clinical trials. Currently, their potential benefits include provision of mature cell types through differentiation, and secretion of various types of paracrine signaling molecules. Even though research on these cells has spanned some decades now, surprisingly, their therapeutic potential has not been fully translated into clinical practice yet, which calls for further understanding of their intrinsic nature and modes of action. In this review, after discussing pieces of evidence that suggest that some perivascular cells may exhibit mesenchymal stem cell characteristics

Indexed as

M2 macrophagesmesenchymal stem cellsmesenchymal stromal cellsMSCspericytesperivascular cellswound healing

Identifiers

PMID36936686
PMCPMC10017474

What OpenQuestion holds

Textfull text, public
LicenceCC BY
reference markers read12
measurements read5
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.