ReviewBMJ medicine2022
Advances in the diagnosis and early management of gestational trophoblastic disease.
Review in BMJ medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.
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Who cites it
33 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Molecular Basis of Hydatidiform Moles-A Systematic Review.International journal of molecular sciences · 2024Pooled it
- Clinical experience with de-escalated chemotherapy for a subset of high-risk gestational trophoblastic neoplasia at a single institution.International journal of clinical oncology · 2026Article
- Review
- Electrochemical biosensors: a novel approach for rapid and cost-effective hCG monitoring in gestational trophoblastic tumours.RSC advances · 2026Review
- Partial molar pregnancy with a viable co-twin complicated by placenta accreta spectrum: case report.International journal of surgery case reports · 2026Article
- Translating STR-based hydatidiform mole diagnosis into precision care.Virchows Archiv : an international journal of pathology · 2026Article
- Frequency of molar pregnancies in a tertiary care hospital: A review of pathology department records.Pakistan journal of medical sciences · 2026Article
- Article
- A Case Report of Tubal Pregnancy Complicated with Partial Hydatidiform Mole.International journal of women's health · 2026Article
- Appraisal of hydatidiform mole incidence and registration rates in Ireland following the establishment of a National Gestational Trophoblastic Disease Registry.Journal of clinical pathology · 2025Article
- STR genotyping diagnosis of hydatidiform moles: an assessment of 2871 consecutive products of conceptions.Virchows Archiv : an international journal of pathology · 2025Article
- Article
- A Rare Case of Choriocarcinoma With Myometrial Invasion Mimicking Invasive Mole: Case Report.Clinical case reports · 2025Article
- Article
- A Case of Choriocarcinoma Undergoing Laparoscopic Surgery Due to Suspected Peritoneal Pregnancy.Cureus · 2025Article
- Complete Hydatiform Mole with a Coexisting Living Fetus: A Case Report.Healthcare (Basel, Switzerland) · 2025Article
- Morphology combined withJournal of clinical pathology · 2025Article
- Novel scoring system provides high separation of diploidy and triploidy to aid partial hydatidiform mole diagnosis: an adaption ofJournal of clinical pathology · 2025Article
- Association of gestational trophoblastic disease with subsequent development of non-trophoblastic cancer.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2025Article
- Correlation Between Serum and Urine β-hCG in Gestational Trophoblastic Neoplasia: A Step Toward Non-Invasive Disease Monitoring.International journal of women's health · 2025Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Gestational trophoblastic disease describes a group of rare pregnancy related disorders that span a spectrum of premalignant and malignant conditions. Hydatidiform mole (also termed molar pregnancy) is the most common form of this disease. Hydatidiform mole describes an abnormal conceptus containing two copies of the paternal genome, which is classified as partial when the maternal genome is present or complete when the maternal genome is absent. Hydatidiform mole typically presents in the first trimester with irregular vaginal bleeding and can be suspected on ultrasound but confirmation requires histopathological evaluation of the products of conception. Most molar pregnancies resolve without treatment after uterine evacuation, but occasionally the disease persists and develops into gestational trophoblastic neoplasia. Close monitoring of women after molar pregnancy, with regular measurement of human chorionic gonadotrophin concentrations, allows for early detection of malignancy. Given the rarity of the disease, clinical management and treatment is best provided in specialist centres where very high cure rates are achievable. This review looks at advances in the diagnosis and early management of gestational trophoblastic disease and highlights updates to disease classification and clinical guidelines. Use of molecular genotyping for improved diagnostic accuracy and risk stratification is reviewed and future biomarkers for the earlier detection of malignancy are considered.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.