Evidence map›Paper›PMID 36936429›Full record

ArticleFrontiers in genetics2023

DNA methylation patterns associated with breast cancer prognosis that are specific to tumor subtype and menopausal status.

Do Hyun Kim, Alexandra M Binder, Hua Zhou, Su Yon Jung

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In one paragraph

Article in Frontiers in genetics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Do Hyun KimDepartment of Biostatistics, Fielding School of Public Health, University of California, Los Angeles, Los Angeles, CA, United States.
Alexandra M BinderCancer Epidemiology Program, University of Hawaii Cancer Center, Honolulu, HI, United States.
Hua ZhouDepartment of Biostatistics, Fielding School of Public Health, University of California, Los Angeles, Los Angeles, CA, United States.
Su Yon JungTranslational Sciences Section, School of Nursing, University of California, Los Angeles, Los Angeles, CA, United States.

Funding

Training Grant in Genomic Analysis and InterpretationT32HG002536 · NHGRI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Valerie A Arboleda, Harold Pimentel · 2002 to 2026
$8.6M
Genomics, GPUs, and Next Generation Computational StatisticsR01HG006139 · NHGRI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI SOBEL, ERIC · 2011 to 2023
$5.1M
Modeling, Inference, and Optimization for Genomic and Biomedical Big DataR35GM141798 · NIGMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI LANGE, KENNETH L · 2021 to 2025
$2.7M
Insulin-Resistance Genetic and Epigenetic Variants and Their Interactions with Lifestyle Factors in Postmenopausal Breast CancerK01NR017852 · NINR · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI JUNG, SU YON · 2019 to 2021
$289k
NHGRI NIH HHS R01 HG006139NHGRI NIH HHS T32 HG002536NIGMS NIH HHS R35 GM141798NINR NIH HHS K01 NR017852
6 · The paper itself

Abstract

Tumor subtype and menopausal status are strong predictors of breast cancer (BC) prognosis. We aimed to find and validate subtype- or menopausal-status-specific changes in tumor DNA methylation (DNAm) associated with all-cause mortality or BC progression. Associations between site-specific tumor DNAm and BC prognosis were estimated among The Cancer Genome Atlas participants (

Indexed as

breast cancerDNA methylation signaturesmenopausesubtypessurvival and prognosis

Identifiers

PMID36936429
PMCPMC10018014

What OpenQuestion holds

Textfull text, public
LicenceCC BY
reference markers read2
measurements read20
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.