Evidence map›Paper›PMID 36936387›Full record

ArticleSynthetic and systems biotechnology2023

Gaining access to acetyl-CoA by peroxisomal surface display.

Thomas Perrot, Sébastien Besseau, Nicolas Papon, Vincent Courdavault

Abstract read
In one paragraph

Article in Synthetic and systems biotechnology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Thomas PerrotBiomolécules et Biotechnologies Végétales, BBV, EA2106, Université de Tours, Tours, France.
Sébastien BesseauBiomolécules et Biotechnologies Végétales, BBV, EA2106, Université de Tours, Tours, France.
Nicolas PaponUniv Angers, Univ Brest, IRF, SFR ICAT, F-49000, Angers, France.
Vincent CourdavaultBiomolécules et Biotechnologies Végétales, BBV, EA2106, Université de Tours, Tours, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Synthetic biology is constantly making progress for producing compounds on demand. Recently, Yocum and collaborators have developed an outstanding approach based on the anchoring of biosynthetic enzymes to the peroxisomal membrane. This allowed access to an untapped resource of acetyl-CoA and stimulated the synthesis of a valuable polyketide.

Indexed as

2-PS, 2-Pyrone synthaseAcc1, Acetyl-CoA carboxylaseAcetyl-CoACat2, Carnitine acetyl-CoA transferaseCoA, Coenzyme AEnzymes colocalizationPeroxisomal membranePolyketidesSynthetic biologyTAL, Triacetic acid lactone

Identifiers

PMID36936387
PMCPMC10020669

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.