Evidence map›Paper›PMID 36936324›Full record

ReviewACS omega2023

Next-Generation Hydrogels as Biomaterials for Biomedical Applications: Exploring the Role of Curcumin.

Vijay Sagar Madamsetty, Maryam Vazifehdoost, Samira Hossaini Alhashemi, Hesam Davoudi, Ali Zarrabi, Ali Dehshahri, Hojjat Samareh Fekri, Reza Mohammadinejad, Vijay Kumar Thakur

Full text readReview
In one paragraph

Review in ACS omega, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Chemical constituents in the rhizome of Curcuma longa and the pharmacological importance of curcumin hybrids.Medicinal chemistry research : an international journal for rapid communications on design and mechanisms of action of biologically active agents · 2026
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  9. Curcumin in Fibrosis Treatment: A Review.Drug design, development and therapy · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Vijay Sagar MadamsettyDepartment of Biochemistry and Molecular Biology, Mayo Clinic College of Medicine and Science, Jacksonville, Florida 32224, United States.
Maryam VazifehdoostDepartment of Toxicology & Pharmacology, School of Pharmacy, Kerman University of Medical Sciences, Kerman 6718773654, Iran.
Samira Hossaini AlhashemiPharmaceutical Sciences Research Center, Shiraz University of Medical Sciences, Shiraz 7146864685, Iran.
Hesam DavoudiDepartment of Biology, Faculty of Sciences, University of Zanjan, Zanjan 4537138111, Iran.
Ali ZarrabiDepartment of Biomedical Engineering, Faculty of Engineering and Natural Sciences, Istinye University, 34396 Istanbul, Turkey.
Ali DehshahriDepartment of Pharmaceutical Biotechnology, School of Pharmacy, Shiraz University of Medical Sciences, Shiraz 7146864685, Iran.ORCID https://orcid.org/0000-0003-4458-1292
Hojjat Samareh FekriStudent Research Committee, Kerman University of Medical Sciences, Kerman 7619813159, Iran.
Reza MohammadinejadResearch Center of Tropical and Infectious Diseases, Kerman University of Medical Sciences, Kerman 7619813159, Iran.
Vijay Kumar ThakurBiorefining and Advanced Materials Research Center, Scotland's Rural College (SRUC), Kings Buildings, West Mains Road, Edinburgh EH9 3JG, U.K.ORCID https://orcid.org/0000-0002-0790-2264

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Since the first report on the pharmacological activity of curcumin in 1949, enormous amounts of research have reported diverse activities for this natural polyphenol found in the dietary spice turmeric. However, curcumin has not yet been used for human application as an approved drug. The clinical translation of curcumin has been hampered due to its low solubility and bioavailability. The improvement in bioavailability and solubility of curcumin can be achieved by its formulation using drug delivery systems. Hydrogels with their biocompatibility and low toxicity effects have shown a substantial impact on the successful formulation of hydrophobic drugs for human clinical trials. This review focuses on hydrogel-based delivery systems for curcumin and describes its applications as anti-cancer as well as wound healing agents.

Identifiers

PMID36936324
PMCPMC10018697

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.