Evidence map›Paper›PMID 36936078›Full record

ArticleCell reports methods2023

High-yield vesicle-packaged recombinant protein production from

Tara A Eastwood, Karen Baker, Bree R Streather, Nyasha Allen, Lin Wang, Stanley W Botchway, Ian R Brown, Jennifer R Hiscock, Christopher Lennon, Daniel P Mulvihill

Open access · goldFull text read
In one paragraph

Article in Cell reports methods, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
7.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 31 citations in OpenAlex.

  1. Article
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  7. Article
  8. Engineered Membrane Vesicle Production viaACS synthetic biology · 2025
    Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Review
  14. Article
  15. Opportunities for engineering outer membrane vesicles using synthetic biology approaches.Extracellular vesicles and circulating nucleic acids · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Tara A EastwoodSchool of Biosciences, University of Kent, Canterbury, Kent CT2 7NJ, UK.
Karen BakerSchool of Biosciences, University of Kent, Canterbury, Kent CT2 7NJ, UK.
Bree R StreatherSchool of Biosciences, University of Kent, Canterbury, Kent CT2 7NJ, UK.
Nyasha AllenSchool of Biosciences, University of Kent, Canterbury, Kent CT2 7NJ, UK.
Lin WangCentral Laser Facility, Research Complex at Harwell, Science and Technology Facilities Council, Rutherford Appleton Laboratory, Harwell, Didcot, Oxford OX11 0QX, UK.
Stanley W BotchwayCentral Laser Facility, Research Complex at Harwell, Science and Technology Facilities Council, Rutherford Appleton Laboratory, Harwell, Didcot, Oxford OX11 0QX, UK.
Ian R BrownSchool of Biosciences, University of Kent, Canterbury, Kent CT2 7NJ, UK.
Jennifer R HiscockSchool of Chemistry and Forensics, University of Kent, Canterbury, Kent CT2 7NJ, UK.
Christopher LennonFujifilm-Diosynth Biotechnologies UK, Ltd., Belasis Avenue, Billingham TS23 1LH, UK.
Daniel P MulvihillSchool of Biosciences, University of Kent, Canterbury, Kent CT2 7NJ, UK.
University of Kent · GBRutherford Appleton Laboratory · GBFujifilm (United Kingdom) · GB

Funding

Biotechnology and Biological Sciences Research Council BB/L013703/1_D0101Biotechnology and Biological Sciences Research Council BB/S005544/1
6 · The paper itself

Abstract

We describe an innovative system that exports diverse recombinant proteins in membrane-bound vesicles from

Indexed as

Escherichia coliEscherichia coli ProteinsBiotechnologyRecombinant ProteinsEscherichia coli ProteinsRecombinant Proteinsdisulfide bondextracellular vesiclesrecombinant protein

Identifiers

PMID36936078
PMCPMC10014274
OpenAlexW4318984326

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read90
identifiers read2
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.