Evidence map›Paper›PMID 36936055›Full record

ReviewFuture virology2023

Natural killer cells in COVID-19: from infection, to vaccination and therapy.

Alireza Zafarani, Mohammad Hossein Razizadeh, Salar Pashangzadeh, Mohammad Reza Amirzargar, Mahsa Taghavi-Farahabadi, Mohammad Mahmoudi

Open access · greenFull text readReview
In one paragraph

Review in Future virology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
5.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 36 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. NK Cells: A Powerful Squad Versus SARS-CoV-2.International journal of molecular sciences · 2025
    Review
  5. Article
  6. Article
  7. Observational
  8. Off-the-shelf allogeneic natural killer cells for the treatment of COVID-19.Molecular therapy. Methods & clinical development · 2024
    Article
  9. Cxcl10 is required for survival during SARS-CoV-2 infection in mice.bioRxiv : the preprint server for biology · 2024
    Article
  10. Low-frequency CD8NPJ vaccines · 2024
    Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Review
  18. COVID-19 associated with cryptococcosis: a scoping review.Therapeutic advances in infectious disease
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Alireza ZafaraniDepartment of Hematology & Blood Banking, School of Allied Medicine, Iran University of Medical Sciences, Tehran, Iran.ORCID https://orcid.org/0009-0002-1797-2458
Mohammad Hossein RazizadehDepartment of Virology, Faculty of Medicine, Iran University of Medical Sciences, Tehran, Iran.ORCID https://orcid.org/0000-0003-3232-6163
Salar PashangzadehIranian Research Center for HIV/AIDS, Iranian Institute for Reduction of High-Risk Behaviors, Tehran University of Medical Sciences, Tehran, Iran.ORCID https://orcid.org/0000-0002-0968-6374
Mohammad Reza AmirzargarDepartment of Hematology & Blood Banking, School of Allied Medicine, Iran University of Medical Sciences, Tehran, Iran.ORCID https://orcid.org/0000-0001-9217-8196
Mahsa Taghavi-FarahabadiDepartment of Immunology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.ORCID https://orcid.org/0000-0003-4466-889X
Mohammad MahmoudiDepartment of Immunology, School of Medicine, Iran University of Medical Sciences, Tehran, 1449614535, Iran.ORCID https://orcid.org/0000-0002-1515-4841
Iran University of Medical Sciences · IRIranian Institute for Health Sciences Research · IRTehran University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Natural killer (NK) cells are among the most important innate immunity members, which are the first cells that fight against infected cells. The function of these cells is impaired in patients with COVID-19 and they are not able to prevent the spread of the disease or destroy the infected cells. Few studies have evaluated the effects of COVID-19 vaccines on NK cells, though it has been demonstrated that DNA vaccines and BNT162b2 can affect NK cell response. In the present paper, the effects of SARS-CoV-2 on the NK cells during infection, the effect of vaccination on NK cells, and the NK cell-based therapies were reviewed.

Indexed as

COVID-19exhaustionNK cellsSARS-CoV-2vaccination

Identifiers

PMID36936055
PMCPMC10013930
OpenAlexW4324143427

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read3
identifiers read12
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.