Evidence map›Paper›PMID 36936034›Full record

ArticleWater2023

Arsenite Methyltransferase Is an Important Mediator of Hematotoxicity Induced by Arsenic in Drinking Water.

Sebastian Medina, Haikun Zhang, Laura V Santos-Medina, Zachary A Yee, Kaitlin J Martin, Guanghua Wan, Alicia M Bolt, Xixi Zhou, Miroslav Stýblo, Ke Jian Liu

Open access · goldFull text read
In one paragraph

Article in Water, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.0field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Metallic trace elements in marine sponges living in a semi-enclosed tropical lagoon.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2024
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Sebastian MedinaDepartment of Pharmaceutical Sciences, The University of New Mexico College of Pharmacy, Albuquerque, NM 87131, USA.
Haikun ZhangDepartment of Pharmaceutical Sciences, The University of New Mexico College of Pharmacy, Albuquerque, NM 87131, USA.
Laura V Santos-MedinaDepartment of Biology, New Mexico Highlands University, Las Vegas, NM 87701, USA.
Zachary A YeeDepartment of Biology, New Mexico Highlands University, Las Vegas, NM 87701, USA.
Kaitlin J MartinDepartment of Biology, New Mexico Highlands University, Las Vegas, NM 87701, USA.
Guanghua WanDepartment of Pharmaceutical Sciences, The University of New Mexico College of Pharmacy, Albuquerque, NM 87131, USA.
Alicia M BoltDepartment of Pharmaceutical Sciences, The University of New Mexico College of Pharmacy, Albuquerque, NM 87131, USA.
Xixi ZhouDepartment of Pharmaceutical Sciences, The University of New Mexico College of Pharmacy, Albuquerque, NM 87131, USA.
Miroslav StýbloDepartment of Nutrition, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
Ke Jian LiuDepartment of Pharmaceutical Sciences, The University of New Mexico College of Pharmacy, Albuquerque, NM 87131, USA.
University of New Mexico · USNew Mexico Highlands University · USUniversity of North Carolina at Chapel Hill · US

Funding

NM-INBRE Sequencing and Bioinformatics CoreP20GM103451 · NIGMS · NEW MEXICO STATE UNIVERSITY LAS CRUCES · PI Charlotte C. Gard · 2012 to 2026
$61.2M
UNC-CH CENTER FOR ENVIRONMENTAL HEALTH &SUSCEPTIBILITYP30ES010126 · NIEHS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Hazel B Nichols · 2001 to 2026
$36.3M
University of New Mexico Center for Metals in Biology and Medicine - equipment supplementP20GM130422 · NIGMS · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI Sebastian Medina · 2020 to 2026
$20.4M
UNM Metals Exposure and Toxicity Assessment on tribal Lands in the Southwest (METALS) Superfund Research ProgramP42ES025589 · NIEHS · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI HUDSON, LAURIE G · 2017 to 2025
$16.4M
Pilot Project CoreP30ES032755 · NIEHS · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI FENG, CHANGJIAN (JIM) · 2022 to 2025
$5.2M
The Role of Biotransformation in Arsenic-Induced HematotoxicityR01ES029369 · NIEHS · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI LIU, KE JIAN · 2018 to 2022
$1.8M
Environmental Arsenic Exposure and HematotoxicityR16GM146669 · NIGMS · NEW MEXICO HIGHLANDS UNIVERSITY · PI MEDINA, SEBASTIAN · 2022 to 2023
$371k
NIEHS NIH HHS P30 ES010126NIEHS NIH HHS P30 ES032755NIEHS NIH HHS P42 ES025589NIEHS NIH HHS R01 ES029369NIGMS NIH HHS P20 GM103451NIGMS NIH HHS P20 GM130422NIGMS NIH HHS R16 GM146669
6 · The paper itself

Abstract

Chronic arsenic exposures via the consumption of contaminated drinking water are clearly associated with many deleterious health outcomes, including anemia. Following exposure, trivalent inorganic arsenic (As

Indexed as

anemiaarsenicarsenic (+III oxidation state) methyltransferase (As3MT)arsenite (AsIII)biotransformationred blood cells

Identifiers

PMID36936034
PMCPMC10019457
OpenAlexW4317738849

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read19
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.