ArticleInternational journal of ophthalmology2023
Choroidal thickness, myopia, and myopia control interventions in children: a Meta-analysis and systemic review.
Article in International journal of ophthalmology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 4 of them syntheses that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Effectiveness of orthokeratology in controlling myopia in adolescents aged 6-18 years: a systematic review and meta-analysis.International ophthalmology · 2026Pooled it
- Repeated low-level red-light therapy vs. conventional treatments for myopic control in children: a systematic review and meta-analysis.Scientific reports · 2025Pooled it
- Impact of atropine on changes in choroidal thickness in children with myopia: a meta-analysis of randomized controlled trials.Frontiers in medicine · 2025Pooled it
- Effects of atropine on choroidal thickness in myopic children: a meta-analysis.Frontiers in pharmacology · 2024Pooled it
- Effect of 0.01% Atropine on Choroidal Thickness and Ocular Growth in Pre-myopic Children.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2026Trial
- Effect of Lutein Ester Supplement on Choroidal Thickness in Children: A Randomized Controlled Trial.Translational vision science & technology · 2025Trial
- Short-Term Effect of Stimulating the Pterygopalatine Ganglion Via Electroacupuncture on Choroidal Structure in Human Subjects.Translational vision science & technology · 2024Trial
- Ocular Blood Flow in Eyes with Myopia and Glaucoma: From Pathophysiology to Clinical Implications.Journal of clinical medicine · 2026Review
- Macular, choroidal, and peripapillary OCT parameters in portuguese schoolchildren: normative data and associations with refractive status.Journal of optometry · 2026Article
- Neuro-ophthalmic review on pediatric myopia: Advancing from refraction to a brain-centric model of axial growth.World journal of clinical pediatrics · 2026Review
- Choroidal structural and perfusion characteristics across refractive groups in children.Frontiers in medicine · 2026Article
- Efficacy and safety of orthokeratology sequentially combined with escalating atropine concentrations for myopia control in children.Scientific reports · 2025Article
- Baseline ocular biometrics in children with orthokeratology-induced axial length reduction or elongation.BMC ophthalmology · 2025Article
- IMI-Instrumentation for Myopia Management.Investigative ophthalmology & visual science · 2025Review
- Efficacy and factors influencing toric orthokeratology lenses in managing moderate to high astigmatic myopia.Optometry and vision science : official publication of the American Academy of Optometry · 2025Article
- Thicker peripapillary choroid may be associated with behavioral factors in Tokyo's children.Scientific reports · 2025Article
- The association between subfoveal choroidal thickness and refractive error in Taiwanese children: A cross-sectional study.PloS one · 2025Article
- The Macular Choroidal Thickness in Danish Children with Myopia After Two-Year Low-Dose Atropine and One-Year Wash-Out: A Placebo-Controlled, Randomized Clinical Trial.Ophthalmology and therapy · 2024Article
- The optimal atropine concentration for myopia control in Chinese children: a systematic review and network Meta-analysis.International journal of ophthalmology · 2024Article
- Digital measuring the ocular morphological parameters of guinea pig eyeInternational journal of ophthalmology · 2024Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo investigate changes of choroidal thickness (ChT) in children with myopia and the effect of current myopia control interventions on ChT.
methodsMajor literature databases were searched for studies relevant to myopia in children. All studies used swept-source optical coherence tomography (SS-OCT) or enhanced depth imaging optical coherence tomography (EDI-OCT) to measure the ChT value. The weighted mean difference (WMD) and 95% confidence interval (CI) were pooled to evaluate ChT in myopia children.
resultsA total of 11 eligible articles, including 1693 myopic and 1132 non-myopic eyes, were included in the first Meta-analysis. The sub-foveal choroidal thickness (SFCT; WMD=-40.06, 95%CI, -59.36 to -20.75,
conclusionThe ChT in myopic eyes is thinner than that in non-myopic eyes in pediatric population. Myopia control interventions including OK and OKA lead to ChT thickening, but other treatments such as 0.01% atropine did not show an increase in ChT.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.