ArticleAlzheimer's & dementia (Amsterdam, Netherlands)
Statistical harmonization of everyday functioning and dementia-related behavioral measures across nine surveys and trials.
Article in Alzheimer's & dementia (Amsterdam, Netherlands). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
4 citing papers in PubMed.
- Bidirectional data harmonization across the multiple chronic disease disparities research consortium: A pipeline description of opportunities and challenges.Journal of biomedical informatics · 2026Article
- Semantic search helper: A tool based on the use of embeddings in multi-item questionnaires as a harmonization opportunity for merging large datasets - A feasibility study.European psychiatry : the journal of the Association of European Psychiatrists · 2025Article
- Statistical harmonization of everyday functioning and dementia-related behavioral measures across nine surveys and trials.Alzheimer's & dementia (Amsterdam, Netherlands)Article
- Harmonizing late-life cognitive performance data across two population-based cohort studies: The Health and Retirement Study and National Health and Aging Trends Study.Alzheimer's & dementia (Amsterdam, Netherlands)Article
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Authors and funding
3 authors.
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Abstract
Introduction: Efforts to harmonize measures of everyday function and dementia-related behaviors are needed to synthesize across studies in dementia research. There have been some psychometric attempts to harmonize everyday function for secondary analysis, but far less for dementia-related behaviors. Methods: Statistical co-calibration was performed to generate factor scores representing everyday function and dementia-related behaviors for participants with dementia. We evaluated convergent criterion validity of factor scores and mapped the scores onto established clinical instruments. Results: Factor analyses of included items fit well to available data. Harmonized factors showed expected associations with the Global Clinical Dementia Rating (CDR) score, with greater impairment (higher Global CDR score) corresponding to higher (more severe) levels on factor scores. Discussion: We used large, well-characterized samples to derive harmonized factors representing everyday functions and dementia-related behaviors. These harmonized factors can be used to tackle questions about dementia phenotypes which require either large samples or unique subpopulations.
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