Evidence map›Paper›PMID 36935752›Full record

ReviewFrontiers in physiology2023

Overview of the structure and function of the dopamine transporter and its protein interactions.

Binod Nepal, Sanjay Das, Maarten E Reith, Sandhya Kortagere

Open access · goldFull text readReview
In one paragraph

Review in Frontiers in physiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
5.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 39 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Binod NepalDepartment of Microbiology and Immunology, Drexel University College of Medicine, Philadelphia, PA, United States.
Sanjay DasDepartment of Microbiology and Immunology, Drexel University College of Medicine, Philadelphia, PA, United States.
Maarten E ReithDepartment of Psychiatry, New York University School of Medicine, New York City, NY, United States.
Sandhya KortagereDepartment of Microbiology and Immunology, Drexel University College of Medicine, Philadelphia, PA, United States.
Drexel University · USNew York University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The dopamine transporter (DAT) plays an integral role in dopamine neurotransmission through the clearance of dopamine from the extracellular space. Dysregulation of DAT is central to the pathophysiology of numerous neuropsychiatric disorders and as such is an attractive therapeutic target. DAT belongs to the solute carrier family 6 (SLC6) class of Na

Indexed as

allosteric modulatorsdopamine transporterinward-openoligomerizationoutward-openpost translational modificationstatα-synuclein

Identifiers

PMID36935752
PMCPMC10020207
OpenAlexW4323045153

What OpenQuestion holds

Textfull text, public
LicenceCC BY
reference markers read58
measurements read25
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.