Evidence map›Paper›PMID 36935652›Full record

ReviewFrontiers in neuroanatomy2023

Cortico-thalamic development and disease: From cells, to circuits, to schizophrenia.

Marilyn M Angulo Salavarria, Claudia Dell'Amico, Armando D'Agostino, Luciano Conti, Marco Onorati

Full text readReview
In one paragraph

Review in Frontiers in neuroanatomy, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Loss of function of the chromatin remodeling geneProceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  2. Article
  3. Article
  4. Thalamus-cortex interactions drive cell type-specific cortical development in human pluripotent stem cell-derived assembloids.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. Brain organoid protocols and limitations.Frontiers in cellular neuroscience · 2024
    Review
  10. Motor Dysfunctions in Fibromyalgia Patients: The Importance of Breathing.Open access rheumatology : research and reviews · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Marilyn M Angulo SalavarriaUnit of Cell and Developmental Biology, Department of Biology, University of Pisa, Pisa, Italy.
Claudia Dell'AmicoUnit of Cell and Developmental Biology, Department of Biology, University of Pisa, Pisa, Italy.
Armando D'AgostinoDepartment of Health Sciences, University of Milan, Milan, Italy.
Luciano ContiDepartment of Cellular, Computational, and Integrative Biology, University of Trento, Trento, Italy.
Marco OnoratiUnit of Cell and Developmental Biology, Department of Biology, University of Pisa, Pisa, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The human brain is the most complex structure generated during development. Unveiling the ontogenesis and the intrinsic organization of specific neural networks may represent a key to understanding the physio-pathological aspects of different brain areas. The cortico-thalamic and thalamo-cortical (CT-TC) circuits process and modulate essential tasks such as wakefulness, sleep and memory, and their alterations may result in neurodevelopmental and psychiatric disorders. These pathologies are reported to affect specific neural populations but may also broadly alter physiological connections and thus dysregulate brain network generation, communication, and function. More specifically, the CT-TC system is reported to be severely affected in disorders impacting superior brain functions, such as schizophrenia (SCZ), bipolar disorder, autism spectrum disorders or epilepsy. In this review, the focus will be on CT development, and the models exploited to uncover and comprehend its molecular and cellular mechanisms. In parallel to animal models, still fundamental to unveil human neural network establishment, advanced

Indexed as

cerebral cortexneurodevelopmentorganoidsschizophreniathalamus

Identifiers

PMID36935652
PMCPMC10019505

What OpenQuestion holds

Textfull text, public
LicenceCC BY
reference markers read11
measurements read3
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.