Evidence map›Paper›PMID 36935490›Full record

ArticleBMC plant biology2023

Comparative proteome profiles of Polygonatum cyrtonema Hua rhizomes (Rhizoma Ploygonati) in response to different levels of cadmium stress.

Rong Song, Bei Yan, Jin Xie, Li Zhou, Rui Xu, Jia Min Zhou, Xiong Hui Ji, Zi Li Yi

Open access · goldFull text read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC plant biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
4.0field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Rong SongCollege of Bioscience and Biotechnology, Hunan Agricultural University, Changsha, 410128, Hunan, China.
Bei YanCollege of Plant Protection, Hunan Agricultural University, Changsha, 410128, Hunan, China.
Jin XieInstitute of Agricultural Environment and Ecology, Hunan Academy of Agricultural Sciences, Changsha, 410125, Hunan, China.
Li ZhouInstitute of Agricultural Environment and Ecology, Hunan Academy of Agricultural Sciences, Changsha, 410125, Hunan, China.
Rui XuInstitute of Agricultural Environment and Ecology, Hunan Academy of Agricultural Sciences, Changsha, 410125, Hunan, China.
Jia Min ZhouInstitute of Agricultural Environment and Ecology, Hunan Academy of Agricultural Sciences, Changsha, 410125, Hunan, China.
Xiong Hui JiInstitute of Agricultural Environment and Ecology, Hunan Academy of Agricultural Sciences, Changsha, 410125, Hunan, China.
Zi Li YiCollege of Bioscience and Biotechnology, Hunan Agricultural University, Changsha, 410128, Hunan, China. yizili889@163.com.
Hunan Academy of Agricultural Sciences · CNHunan Agricultural University · CN

Funding

National key research and development program of China during the "14th Five-Year Plan" 2022YFD1700103The Science and Technology development program guided by the central government of Hunan Province 2022ZYC04The Science and Technology Plan Projects of Hunan Province 2020SK2033
6 · The paper itself

Abstract

backgroundThe Polygonatum cyrtonema Hua rhizomes (also known as Rhizoma Polygonati, RP) are consumed for their health benefits. The main source of the RP is wild P. cyrtonema populations in the Hunan province of China. However, the soil Cadmium (Cd) content in Huanan is increasing, thus increasing the risks of Cd accumulation in RP which may end up in the human food chain. To understand the mechanism of Cd accumulation and resistance in P. cyrtonema, we subjected P. cyrtonema plants to four levels of Cd stress [(D2) 1, (D3) 2, (D4) 4, and (D5) 8 mg/kg)] compared to (D1) 0.5 mg/kg.

resultsThe increase in soil Cd content up to 4 mg/kg resulted in a significant increase in tissue (root hair, rhizome, stem, and leaf) Cd content. The increase in Cd concentration variably affected the antioxidant enzyme activities. We could identify 14,171 and 12,115 protein groups and peptides, respectively. There were 193, 227, 260, and 163 differentially expressed proteins (DEPs) in D2, D3, D4, and D5, respectively, compared to D1. The number of downregulated DEPs increased with an increase in Cd content up to 4 mg/kg. These downregulated proteins belonged to sugar biosynthesis, amino acid biosynthesis-related pathways, and secondary metabolism-related pathways. Our results indicate that Cd stress increases ROS generation, against which, different ROS scavenging proteins are upregulated in P. cyrtonema. Moreover, Cd stress affected the expression of lipid transport and assembly, glycolysis/gluconeogenesis, sugar biosynthesis, and ATP generation.

conclusionThese results suggest that an increase in soil Cd content may end up in Huangjing. Cadmium stress initiates expression changes in multiple pathways related to energy metabolism, sugar biosynthesis, and secondary metabolite biosynthesis. The proteins involved in these pathways are potential candidates for manipulation and development of Cd stress-tolerant genotypes.

Indexed as

CadmiumPolygonatumHumansProteomeReactive Oxygen SpeciesRhizomeSugarsCadmiumProteomeReactive Oxygen SpeciesSugarsATP generationCadmium stressDIA technologyHuangjingRhizome Cd contentSugar biosynthesis

Identifiers

PMID36935490
PMCPMC10026435
OpenAlexW4327892718

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.