Evidence map›Paper›PMID 36935472›Full record

ArticleAging clinical and experimental research2023

On frailty and accelerated aging during SARS-Cov-2: senescence.

Ursula Müller-Werdan, M Cristina Polidori, Andreas Simm

Open access · hybridFull text read
In one paragraph

Article in Aging clinical and experimental research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Influenza vaccination in older people: a geriatrician's perspective.Aging clinical and experimental research · 2025
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Ursula Müller-Werdan *Department of Geriatrics and Medical Gerontology, Charité - Universitätsmedizin Berlin and EGZB, Berlin, Germany.
M Cristina Polidori *Department II of Internal Medicine and Center for Molecular Medicine Cologne, Ageing Clinical Research, University of Cologne, Faculty of Medicine and University Hospital Cologne, Cologne, Germany. maria.polidori-nelles@uk-koeln.de.ORCID http://orcid.org/0000-0002-8881-904X
Andreas Simm *Clinic for Cardiac Surgery, University Hospital Halle (Saale), Martin-Luther-University Halle-Wittenberg, Halle (Saale), Germany.
Charité - Universitätsmedizin Berlin · DEMartin Luther University Halle-Wittenberg · DEUniversity of Cologne · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The COVID-19 pandemic is a burden for the worldwide healthcare systems. Whereas a clear age-dependent mortality can be observed, especially multimorbid and frail persons are at an increased risk. As bio-functional rather than calendrical age is in the meanwhile known to play a crucial role for COVID-19-related outcomes, aging-associated risk factors, overall prognosis and physiological age-related changes should be systematically considered for clinical decision-making. In this overview, we focus on cellular senescence as a major factor of biological aging, associated with organ dysfunction and increased inflammation (inflammaging).

Indexed as

COVID-19FrailtyAgingCellular SenescenceHumansPandemicsSARS-CoV-2AgingBiological AgeCoronavirusCOVID-19FrailtyInflammagingSenescence

Identifiers

PMID36935472
PMCPMC10025062
OpenAlexW4327859674

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read2
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.