Evidence map›Paper›PMID 36935354›Full record

ReviewChembiochem : a European journal of chemical biology2023

Glycosphingolipid and Glycosylphosphatidylinositol Affect Each Other in and on the Cell.

Zhongwu Guo

Open access · greenAbstract readReview
In one paragraph

Review in Chembiochem : a European journal of chemical biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Zhongwu GuoDepartment of Chemistry, University of Florida, Gainesville, Florida, 32811, USA.ORCID 0000-0001-5302-6456
University of Florida · US

Funding

Synthetic and Biological Studies of GPI Conjugates and GPI Anchorage to Cell MembranesR35GM131686 · NIGMS · UNIVERSITY OF FLORIDA · PI Zhongwu Guo · 2019 to 2026
$2.5M
NIGMS NIH HHS R35 GM131686
6 · The paper itself

Abstract

Glycosphingolipid (GSL) and glycosylphosphatidylinositol (GPI) are the two major glycolipids expressed by eukaryotic cells, and their metabolisms share the same machineries. Moreover, both GSLs and GPI-anchored proteins (GPI-APs) are localized in the cholesterol-rich regions, namely the lipid rafts, of the cell membrane, where many other signaling molecules are compartmentalized as well. Therefore, the interaction between GSLs and GPI-APs and their interactions with other molecules in the lipid rafts are inevitable. This review is focused on the influences of GSLs and GPI-APs on each other's biosynthesis, trafficking, cell membrane distribution, and biological functions, such as signal transduction.

Indexed as

GlycosphingolipidsGlycosylphosphatidylinositolsCell MembraneMembrane MicrodomainsProteinsGlycosphingolipidsGlycosylphosphatidylinositolsProteinsglycolipidsglycosphingolipidsglycosylphosphatidylinositolglycosylphosphatidylinositol-anchored proteinslipid rafts

Identifiers

PMID36935354
PMCPMC10330729
OpenAlexW4327895120

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.